Recent Patents on Anti-Cancer Drug Discovery

Cancer Stem Cells and their Management in Cancer Therapy

Volume: 15   Issue: 3
Pp: 212-227
Suzan Shenouda, Ketan Kulkarni, Yasser Abuetabh and Consolato Sergi *
DOI: 10.2174/1574892815666200713145931

Combining PD-1 Inhibitor with VEGF/VEGFR2 Inhibitor in Chemotherapy: Report of a Patient with End-Stage Cholangiocarcinoma and Review of Literature

Volume: 16   Issue: 1
Pp: 101-107
Zhenjiang Ma, Heping Li and Liangshuai Liu*
DOI: 10.2174/1574892815999201231215311

Anti-Cancer Effect of Melatonin via Downregulation of Delta-like Ligand 4 in Estrogen-Responsive Breast Cancer Cells

Volume: 15   Issue: 4
Pp: 329-340
Ali Rajabi, Ali Saber, Mahsa Pourmahdi, Ali Emami, Reyhaneh Ravanbakhsh, Amir Khodavirdipour, Mehran Khodaei, Molood Akbarzadeh, Sepehr Abdolahi, Mohammad Ali Hosseinpourfeizi and Reza Safaralizadeh*
DOI: 10.2174/1574892815666200929145236

Novel Selective Histone Deacetylase 6 (HDAC6) Inhibitors: A Patent Review (2016-2019) promotion: free to download

Volume: 15   Issue: 1
Pp: 32-48
Xingrui He, Zhen Li, Xiao-Tao Zhuo, Zi Hui, Tian Xie* and Xiang-Yang Ye*
DOI: 10.2174/1574892815666200217125419

Phytochemicals as PI3K/ Akt/ mTOR Inhibitors and Their Role in Breast Cancer Treatment promotion: free to download

Volume: 15   Issue: 3
Pp: 188-199
Arunaksharan Narayanankutty*
DOI: 10.2174/1574892815666200910164641

Monoclonal Antibodies, Bispecific Antibodies and Antibody-Drug Conjugates in Oncohematology promotion: free to download

Volume: 15   Issue: 4
Pp: 272-292
Romeo G. Mihăilă*
DOI: 10.2174/1574892815666200925120717

Potential Therapeutic Targets of Curcumin, Most Abundant Active Compound of Turmeric Spice: Role in the Management of Various Types of Cancer

Volume: 16   Issue: 1
Pp: 3-29
Saleh A. Almatroodi, Mansoor Ali Syed and Arshad Husain Rahmani*
DOI: 10.2174/1574892815999201102214602

Next Generation Sequencing in the Management of Leptomeningeal Metastases of Non-Small Cell Lung Cancer: A Case Report and Literature Review

Volume: 16   Issue: 1
Pp: 108-116
Shuo Li*, Linping Ke*, Xue Meng, Haiyan Zhou, Xiqin Zhang, Huaguo Wu, Jinming Yu* and Hui Zhang*
DOI: 10.2174/1574892815666201127114224

Recent Patents on the Development of c-Met Kinase Inhibitors

Volume: 15   Issue: 3
Pp: 228-238
Xiangming Xu and Lei Yao*
DOI: 10.2174/1574892815666200630102344

Anti-EGFR-mAb and 5-Fluorouracil Conjugated Polymeric Nanoparticles for Colorectal Cancer

Volume: 16   Issue: 1
Pp: 84-100
Sankha Bhattacharya*
DOI: 10.2174/1574892815666201221121859

Anti-EGFR Binding Nanobody Delivery System to Improve the Diagnosis and Treatment of Solid Tumours promotion: free to download

Volume: 15   Issue: 3
Pp: 200-211
Long Wang, Gengyuan Zhang, Long Qin, Huili Ye, Yan Wang, Bo Long and Zuoyi Jiao*
DOI: 10.2174/1574892815666200904111728

Autophagy and Ubiquitination as Two Major Players in Colorectal Cancer: A Review on Recent Patents

Volume: 15   Issue: 2
Pp: 143-153
Javad Saffari-Chaleshtori, Majid Asadi-Samani, Maryam Rasouli and Sayed Mohammad Shafiee*
DOI: 10.2174/1574892815666200630103626

Effect of PI3K/AKT/mTOR Signaling Pathway on Regulating and Controlling the Anti-Invasion and Metastasis of Hepatoma Cells by Bufalin

Volume: 16   Issue: 1
Pp: 54-65
Xia Sheng, Pengfei Zhu, Yi Zhao, Jinwei Zhang, Haijia Li, Huan Zhao and Jianmin Qin*
DOI: 10.2174/1574892816666210201120324

Modulation of MicroRNAs by Euphorbia Microsciadia Boiss in MDA-MB-231 Cell Line: New Possibilities in Breast Cancer Therapy

Volume: 15   Issue: 2
Pp: 174-184
Mohammad-Reza Mahmoudian-Sani and Majid Asadi-Samani*
DOI: 10.2174/1574892815666200630102944

Recent Advances in the Development of Selective Mcl-1 Inhibitors for the Treatment of Cancer (2017-Present) promotion: free to download

Volume: 15   Issue: 4
Pp: 306-320
Ying Fan, Xuben Hou* and Hao Fang*
DOI: 10.2174/1574892815666200916124641

RNA Splicing: Basic Aspects Underlie Antitumor Targeting

Volume: 15   Issue: 4
Pp: 293-305
Alzahraa A.M. Fergany* and Victor V. Tatarskiy
DOI: 10.2174/1574892815666200908122402

Terpenes with Antitumor Activity: A Patent Review

Volume: 15   Issue: 4
Pp: 321-328
Juliana de Vasconcelos Cerqueira Braz*, José Adão Carvalho Nascimento Júnior and Mairim Russo Serafini
DOI: 10.2174/1574892815666201002162315

Immunological Mechanism and Clinical Application of PAMP Adjuvants

Volume: 16   Issue: 1
Pp: 30-43
Yu Yan, Dan Yao and Xiaoyu Li*
DOI: 10.2174/1574892816666210201114712

Construction and Validation of a Nomogram for Predicting Progression- Free Survival in Patients with Early-Stage Testicular Germ Cell Tumor

Volume: 16   Issue: 1
Pp: 44-53
Jin-Guo Chen, Jing-Quan Wang, Tian-Wen Peng, Zhe-Sheng Chen* and Shan-Chao Zhao*
DOI: 10.2174/1574892816666210211092108

The JPJDF has Synergistic Effect with Fluoropyrimidine in the Maintenance Therapy for Metastatic Colorectal Cancer

Volume: 15   Issue: 3
Pp: 257-269
Xiaoling Fu*, Yanbo Zhang, Lisheng Chang, Dengcheng Hui, Ru Jia, Ningning Liu, Huayue Zhang, Gang Han, Zhifen Han, Yuan Li, Hui Liu, Huirong Zhu and Qi Li*
DOI: 10.2174/1574892815666200717141205