Recent Patents on Anti-Cancer Drug Discovery

Death-Associated Protein Kinase 1 as a Promising Drug Target in Cancer and Alzheimer’s Disease open Access plus

Volume: 14   Issue: 2
Pp: 144-157
Dongmei Chen, Xiao Z. Zhou* and Tae H. Lee*
DOI:10.2174/1574892814666181218170257

From Antimicrobial to Anticancer Peptides: The Transformation of Peptides open Access plus

Volume: 14   Issue: 1
Pp: 70-84
Yuan Qin, Zuo D. Qin, Jing Chen, Che G. Cai, Ling Li, Lu Y. Feng, Zheng Wang, Gregory J. Duns, Nong Y. He, Zhe S. Chen* and Xiao F. Luo*
DOI:10.2174/1574892814666190119165157

Chimeric Antigen Receptor T Cell Immunotherapy for Tumor: A Review of Patent Literatures open Access plus

Volume: 14   Issue: 1
Pp: 60-69
Manxue Fu and Liling Tang*
DOI:10.2174/1574892814666190111120908

New Anti-Cancer Strategies in Testicular Germ Cell Tumors open Access plus

Volume: 14   Issue: 1
Pp: 53-59
Paolo Chieffi*, Marco De Martino and Francesco Esposito
DOI:10.2174/1574892814666190111120023

Tocotrienols and Cancer: From the State of the Art to Promising Novel Patents open Access plus

Volume: 14   Issue: 1
Pp: 5-18
Fabrizio Fontana, Michela Raimondi, Monica Marzagalli, Roberta M. Moretti, Marina Montagnani Marelli and Patrizia Limonta*
DOI:10.2174/1574892814666190116111827

Tobacco Smoking: Risk to Develop Addiction, Chronic Obstructive Pulmonary Disease, and Lung Cancer open Access plus

Volume: 14   Issue: 1
Pp: 39-52
Alessia Santoro, Carlo Tomino, Giulia Prinzi, Palma Lamonaca, Vittorio Cardaci, Massimo Fini and Patrizia Russo*
DOI:10.2174/1574892814666190102122848

Purinergic P2X7 Receptor: A Cation Channel Sensitive to Tumor Microenvironment open Access plus

Volume: 14   Issue: 1
Pp: 32-38
Giorgia Scarpellino, Tullio Genova and Luca Munaron*
DOI:10.2174/1574892814666190116122256

Contemporary Formulations for Drug Delivery of Anticancer Bioactive Compounds open Access plus

Volume: 14   Issue: 1
Pp: 19-31
Darinka G. Ackova, Katarina Smilkov and Darko Bosnakovski*
DOI:10.2174/1574892814666190111104834

Semi-Synthetic Derivatives of Heliomycin with an Antiproliferative Potency open Access plus

Volume: 13   Issue: 4
Pp: 469-472
Georgy Y. Nadysev, Alexander S. Tikhomirov, Lyubov G. Dezhenkova and Andrey E. Shchekotikhin*
DOI:10.2174/1574892813666180723150542

Amplified Crosstalk Between Estrogen Binding and GFR Signaling Mediated Pathways of ER Activation Drives Responses in Tumors Treated with Endocrine Disruptors open Access plus

Volume: 13   Issue: 4
Pp: 428-444
Zsuzsanna Suba*
DOI:10.2174/1574892813666180720123732

Targeting Metabolism to Counteract Tumor Angiogenesis: A Review of Patent Literature open Access plus

Volume: 13   Issue: 4
Pp: 422-427
Sara Petrillo, Emanuela Tolosano, Luca Munaron and Tullio Genova*
DOI:10.2174/1574892813666180528105023

Anaplastic Lymphoma Kinase in Glioblastoma: Detection/Diagnostic Methods and Therapeutic Options open Access plus

Volume: 13   Issue: 2
Pp: 209-223
Theodosis Kalamatianos, Despoina Denekou, George Stranjalis and Evangelia Papadimitriou*
DOI:10.2174/1574892813666180115151554

Lenvatinib in the Therapy of Aggressive Thyroid Cancer: State of the Art and New Perspectives with Patents Recently Applied open Access plus

Volume: 13   Issue: 2
Pp: 201-208
Silvia M. Ferrari, Ilaria Ruffilli, Marco Centanni, Camilla Virili, Gabriele Materazzi, Magdalini Alexopoulou, Mario Miccoli, Alessandro Antonelli* and Poupak Fallahi
DOI:10.2174/1574892813666180220110729

Targeting Mevalonate Pathway in Cancer Treatment: Repurposing of Statins open Access plus

Volume: 13   Issue: 2
Pp: 184-200
Federica Iannelli, Rita Lombardi, Maria R. Milone, Biagio Pucci, Simona De Rienzo, Alfredo Budillon* and Francesca Bruzzese*
DOI:10.2174/1574892812666171129141211

PARP Inhibitors in Epithelial Ovarian Cancer open Access plus

Volume: 13   Issue: 2
Pp: 145-158
Kristin N. Taylor and Ramez N. Eskander*
DOI:10.2174/1574892813666171204094822

Novel Patents Targeting Interleukin-17A; Implications in Cancer and Inflammation open Access plus

Volume: 13   Issue: 2
Pp: 133-144
Juan F. Santibanez* and Suncica Bjelica
DOI:10.2174/1574892813666180220105958

Use of human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors in Autoimmune Diseases and New Perspectives in Cancer Therapy open Access plus

Volume: 13   Issue: 1
Pp: 86-105
Marco L. Lolli, Stefano Sainas, Agnese C. Pippione, Marta Giorgis, Donatella Boschi and Franco Dosio*
DOI:10.2174/1574892812666171108124218

Nucleic Acid Sensing Machinery: Targeting Innate Immune System for Cancer Therapy open Access plus

Volume: 13   Issue: 1
Pp: 2-17
Sandra Iurescia*, Daniela Fioretti and Monica Rinaldi*
DOI:10.2174/1574892812666171030163804

Strategies to Tackle Radiation Resistance by Penetrating Cancer Stem Cell Line of Scrimmage open Access plus

Volume: 13   Issue: 1
Pp: 18-39
So-Yeon Park, Ji-Young Kim, Youngsoo Jun and Jeong-Seok Nam*
DOI:10.2174/1574892812666171003150410

From a Better Understanding of the Mechanisms of Action of Histone Deacetylases Inhibitors to the Progress of the Treatment of Malignant Lymphomas and Plasma Cell Myeloma open Access plus

Volume: 12   Issue: 4
Pp: 283-295
Romeo G. Mihaila*
DOI:10.2174/1574892812666170920110054

Activating Mutations of ESR1, BRCA1 and CYP19 Aromatase Genes Confer Tumor Response in Breast Cancers Treated with Antiestrogens open Access plus

Volume: 12   Issue: 2
Pp: 136-147
Zsuzsanna Suba*
DOI:10.2174/1574892812666170227110842

Causal Therapy of Breast Cancer Irrelevant of Age, Tumor Stage and ER-Status: Stimulation of Estrogen Signaling Coupled With Breast Conserving Surgery* open Access plus

Volume: 11   Issue: 3
Pp: 254-266
Zsuzsanna Suba
DOI:10.2174/1574892811666160415160211

Aldo-Keto Reductase Family 1 Member B10 Inhibitors: Potential Drugs for Cancer Treatment open Access plus

Volume: 11   Issue: 2
Pp: 184-196
Li Huang, Rongzhang He, Weihao Luo, Yuan-Shan Zhu, Jia Li, Tan Tan, Xi Zhang, Zheng Hu and Dixian Luo
DOI:10.2174/1574892811888160304113346

Cabozantinib in Thyroid Cancer open Access plus

Volume: 10   Issue: 3
Pp: 259-269
Poupak Fallahi, Silvia M. Ferrari, Flavia Di Bari, Gabriele Materazzi, Salvatore Benvenga, Paolo Miccoli and Alessandro Antonelli
DOI:10.2174/1574892810666150708110816

Circulatory Estrogen Level Protects Against Breast Cancer in Obese Women open Access plus

Volume: 8   Issue: 2
Pp: 154-167
Zsuzsanna Suba
DOI:10.2174/1574892811308020004

Regulating TRAIL Receptor-Induced Cell Death at the Membrane: A Deadly Discussion open Access plus

Volume: 6   Issue: 3
Pp: 311-323
Sarah Shirley, Alexandre Morizot and Olivier Micheau
DOI:10.2174/157489211796957757