Recent Patents on Anti-Cancer Drug Discovery


Zhe-Sheng (Jason) Chen
Institute for Biotechnology
College of Pharmacy and Health Sciences
St. John's University
New York, NY

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Most Cited Article

Alkaloids as Anticancer Agents: A Review of Chinese Patents in Recent 5 Years

Volume:15   Issue:1
Pp: 2-13
Hongyu Tao, Ling Zuo, Huanli Xu, Cong Li, Gan Qiao, Mingyue Guo and Xiukun Lin*
DOI: 10.2174/1574892815666200131120618

Novel Selective Histone Deacetylase 6 (HDAC6) Inhibitors: A Patent Review (2016-2019)

Volume:15   Issue:1
Pp: 32-48
Xingrui He, Zhen Li, Xiao-Tao Zhuo, Zi Hui, Tian Xie* and Xiang-Yang Ye*
DOI: 10.2174/1574892815666200217125419

Anti-EGFR Binding Nanobody Delivery System to Improve the Diagnosis and Treatment of Solid Tumours

Volume:15   Issue:3
Pp: 200-211
Long Wang, Gengyuan Zhang, Long Qin, Huili Ye, Yan Wang, Bo Long and Zuoyi Jiao*
DOI: 10.2174/1574892815666200904111728

Developments in the Application of 1,2,3-Triazoles in Cancer Treatment

Volume:15   Issue:2
Pp: 92-112
Katerina I. Slavova, Lozan T. Todorov*, Nataliya P. Belskaya, Mauricio A. Palafox and Irena P. Kostova
DOI: 10.2174/1574892815666200717164457

Recent Patents on the Development of c-Met Kinase Inhibitors

Volume:15   Issue:3
Pp: 228-238
Xiangming Xu and Lei Yao*
DOI: 10.2174/1574892815666200630102344

The Molecular Docking of Flavonoids Isolated from Daucus carota as a Dual Inhibitor of MDM2 and MDMX

Volume:15   Issue:2
Pp: 154-164
Ijaz Muhammad, Noor Rahman, Gul E. Nayab, Sadaf Niaz, Mohibullah Shah, Sahib G. Afridi, Haroon Khan*, Maria Daglia and Esra Capanoglu
DOI: 10.2174/1574892815666200226112506

Feasibility of Repurposing Clioquinol for Cancer Therapy

Volume:15   Issue:1
Pp: 14-31
Raheel Khan, Harras Khan, Yassen Abdullah and Q. Ping Dou*
DOI: 10.2174/1574892815666200227090259

Preface promotion: free to download

Volume:16   Issue:1
Pp: 1-1
Zhe-Sheng (Jason) Chen
DOI: 10.2174/157489281601210324142034

Effect of PI3K/AKT/mTOR Signaling Pathway on Regulating and Controlling the Anti-Invasion and Metastasis of Hepatoma Cells by Bufalin

Volume:16   Issue:1
Pp: 54-65
Xia Sheng, Pengfei Zhu, Yi Zhao, Jinwei Zhang, Haijia Li, Huan Zhao and Jianmin Qin*
DOI: 10.2174/1574892816666210201120324

Immunological Mechanism and Clinical Application of PAMP Adjuvants

Volume:16   Issue:1
Pp: 30-43
Yu Yan, Dan Yao and Xiaoyu Li*
DOI: 10.2174/1574892816666210201114712

The Anti-Proliferative Effect of a Newly-Produced Anti-PSCA-Peptide Antibody by Multiple Bioinformatics Tools, on Prostate Cancer Cells

Volume:16   Issue:1
Pp: 73-83
Milad Chizari, Sajad Fani-Kheshti, Jaleh Taeb, Mohammad M. Farajollahi* and Monireh Mohsenzadegan*
DOI: 10.2174/1574892815999201110212411

Construction and Validation of a Nomogram for Predicting Progression- Free Survival in Patients with Early-Stage Testicular Germ Cell Tumor

Volume:16   Issue:1
Pp: 44-53
Jin-Guo Chen, Jing-Quan Wang, Tian-Wen Peng, Zhe-Sheng Chen* and Shan-Chao Zhao*
DOI: 10.2174/1574892816666210211092108

Next Generation Sequencing in the Management of Leptomeningeal Metastases of Non-Small Cell Lung Cancer: A Case Report and Literature Review

Volume:16   Issue:1
Pp: 108-116
Shuo Li*, Linping Ke*, Xue Meng, Haiyan Zhou, Xiqin Zhang, Huaguo Wu, Jinming Yu* and Hui Zhang*
DOI: 10.2174/1574892815666201127114224

Expression and Clinical Significance of Microtubule-Actin Cross-Linking Factor 1 in Serous Ovarian Cancer

Volume:16   Issue:1
Pp: 66-72
Longyang Liu, Ke Hu, Zhaoyang Zeng, Caiqiu Xu, Jin Lv, Zhongqiu Lin and Bin Wen*
DOI: 10.2174/1574892816666210211091543

Anti-Cancer Effect of Melatonin via Downregulation of Delta-like Ligand 4 in Estrogen-Responsive Breast Cancer Cells

Volume:15   Issue:4
Pp: 329-340
Ali Rajabi, Ali Saber, Mahsa Pourmahdi, Ali Emami, Reyhaneh Ravanbakhsh, Amir Khodavirdipour, Mehran Khodaei, Molood Akbarzadeh, Sepehr Abdolahi, Mohammad Ali Hosseinpourfeizi and Reza Safaralizadeh*
DOI: 10.2174/1574892815666200929145236

In Vitro and In Vivo Evaluation of Novel DTX-Loaded Multifunctional Heparin-Based Polymeric Micelles Targeting Folate Receptors and Endosomes

Volume:15   Issue:4
Pp: 341-359
Moloud Kazemi, Jaber Emami*, Farshid Hasanzadeh, Mohsen Minaiyan, Mina Mirian, Afsaneh Lavasanifar and Mojgan Mokhtari
DOI: 10.2174/1574892815666201006124604

Terpenes with Antitumor Activity: A Patent Review

Volume:15   Issue:4
Pp: 321-328
Juliana de Vasconcelos Cerqueira Braz*, José Adão Carvalho Nascimento Júnior and Mairim Russo Serafini
DOI: 10.2174/1574892815666201002162315

RNA Splicing: Basic Aspects Underlie Antitumor Targeting

Volume:15   Issue:4
Pp: 293-305
Alzahraa A.M. Fergany* and Victor V. Tatarskiy
DOI: 10.2174/1574892815666200908122402