Recent Patents on Anti-Cancer Drug Discovery

Expression of B Cell Translocation Gene 1 Protein in Colon Carcinoma and its Clinical Significance promotion: free to download

Volume:15   Issue:1
Pp: 78-85
Junhe Zhang* and Weihua Dong
DOI: 10.2174/1574892815666200109113114

Alkaloids as Anticancer Agents: A Review of Chinese Patents in Recent 5 Years promotion: free to download

Volume:15   Issue:1
Pp: 2-13
Hongyu Tao, Ling Zuo, Huanli Xu, Cong Li, Gan Qiao, Mingyue Guo and Xiukun Lin*
DOI: 10.2174/1574892815666200131120618

Novel Selective Histone Deacetylase 6 (HDAC6) Inhibitors: A Patent Review (2016-2019) promotion: free to download

Volume:15   Issue:1
Pp: 32-48
Xingrui He, Zhen Li, Xiao-Tao Zhuo, Zi Hui, Tian Xie* and Xiang-Yang Ye*
DOI: 10.2174/1574892815666200217125419

Monoclonal Antibodies, Bispecific Antibodies and Antibody-Drug Conjugates in Oncohematology

Volume:15   Issue:4
Pp: 272-292
Romeo G. Mihăilă*
DOI: 10.2174/1574892815666200925120717

Anti-EGFR Binding Nanobody Delivery System to Improve the Diagnosis and Treatment of Solid Tumours

Volume:15   Issue:3
Pp: 200-211
Long Wang, Gengyuan Zhang, Long Qin, Huili Ye, Yan Wang, Bo Long and Zuoyi Jiao*
DOI: 10.2174/1574892815666200904111728

Developments in the Application of 1,2,3-Triazoles in Cancer Treatment promotion: free to download

Volume:15   Issue:2
Pp: 92-112
Katerina I. Slavova, Lozan T. Todorov*, Nataliya P. Belskaya, Mauricio A. Palafox and Irena P. Kostova
DOI: 10.2174/1574892815666200717164457

Modulation of MicroRNAs by Euphorbia Microsciadia Boiss in MDA-MB-231 Cell Line: New Possibilities in Breast Cancer Therapy

Volume:15   Issue:2
Pp: 174-184
Mohammad-Reza Mahmoudian-Sani and Majid Asadi-Samani*
DOI: 10.2174/1574892815666200630102944

Recent Patents on the Development of c-Met Kinase Inhibitors

Volume:15   Issue:3
Pp: 228-238
Xiangming Xu and Lei Yao*
DOI: 10.2174/1574892815666200630102344

The Molecular Docking of Flavonoids Isolated from Daucus carota as a Dual Inhibitor of MDM2 and MDMX

Volume:15   Issue:2
Pp: 154-164
Ijaz Muhammad, Noor Rahman, Gul E. Nayab, Sadaf Niaz, Mohibullah Shah, Sahib G. Afridi, Haroon Khan*, Maria Daglia and Esra Capanoglu
DOI: 10.2174/1574892815666200226112506

Feasibility of Repurposing Clioquinol for Cancer Therapy

Volume:15   Issue:1
Pp: 14-31
Raheel Khan, Harras Khan, Yassen Abdullah and Q. Ping Dou*
DOI: 10.2174/1574892815666200227090259

Anti-Cancer Effect of Melatonin via Downregulation of Delta-like Ligand 4 in Estrogen-Responsive Breast Cancer Cells

Volume:15   Issue:4
Pp: 329-340
Ali Rajabi, Ali Saber, Mahsa Pourmahdi, Ali Emami, Reyhaneh Ravanbakhsh, Amir Khodavirdipour, Mehran Khodaei, Molood Akbarzadeh, Sepehr Abdolahi, Mohammad Ali Hosseinpourfeizi and Reza Safaralizadeh*
DOI: 10.2174/1574892815666200929145236

In Vitro and In Vivo Evaluation of Novel DTX-Loaded Multifunctional Heparin-Based Polymeric Micelles Targeting Folate Receptors and Endosomes

Volume:15   Issue:4
Pp: 341-359
Moloud Kazemi, Jaber Emami*, Farshid Hasanzadeh, Mohsen Minaiyan, Mina Mirian, Afsaneh Lavasanifar and Mojgan Mokhtari
DOI: 10.2174/1574892815666201006124604

Recent Advances in the Development of Selective Mcl-1 Inhibitors for the Treatment of Cancer (2017-Present)

Volume:15   Issue:4
Pp: 306-320
Ying Fan, Xuben Hou* and Hao Fang*
DOI: 10.2174/1574892815666200916124641

Terpenes with Antitumor Activity: A Patent Review

Volume:15   Issue:4
Pp: 321-328
Juliana de Vasconcelos Cerqueira Braz*, José Adão Carvalho Nascimento Júnior and Mairim Russo Serafini
DOI: 10.2174/1574892815666201002162315

RNA Splicing: Basic Aspects Underlie Antitumor Targeting

Volume:15   Issue:4
Pp: 293-305
Alzahraa A.M. Fergany* and Victor V. Tatarskiy
DOI: 10.2174/1574892815666200908122402

Phytochemicals as PI3K/ Akt/ mTOR Inhibitors and Their Role in Breast Cancer Treatment

Volume:15   Issue:3
Pp: 188-199
Arunaksharan Narayanankutty*
DOI: 10.2174/1574892815666200910164641

The Dichloromethane Fraction of Vernonia cinerea Impart Pro-Apoptotic, Genotoxic, Cell Cycle Arrest, and Drug Efflux Inhibitory Effects on Human Adenocarcinoma Cells

Volume:15   Issue:3
Pp: 239-256
Asmy Appadath Beeran, Nayanabhirama Udupa and Naseer Maliyakkal*
DOI: 10.2174/1574892815999200824122723

The JPJDF has Synergistic Effect with Fluoropyrimidine in the Maintenance Therapy for Metastatic Colorectal Cancer

Volume:15   Issue:3
Pp: 257-269
Xiaoling Fu*, Yanbo Zhang, Lisheng Chang, Dengcheng Hui, Ru Jia, Ningning Liu, Huayue Zhang, Gang Han, Zhifen Han, Yuan Li, Hui Liu, Huirong Zhu and Qi Li*
DOI: 10.2174/1574892815666200717141205

Cancer Stem Cells and their Management in Cancer Therapy

Volume:15   Issue:3
Pp: 212-227
Suzan Shenouda, Ketan Kulkarni, Yasser Abuetabh and Consolato Sergi *
DOI: 10.2174/1574892815666200713145931

Anticancer Potential of Aguerin B, a Sesquiterpene Lactone Isolated from Centaurea behen in Metastatic Breast Cancer Cells

Volume:15   Issue:2
Pp: 165-173
Elaheh Amini, Mohammad Nabiuni, Seyed Bahram Behzad, Danial Seyfi, Farhad Eisvand, Amirhossein Sahebkar* and Abolfazl Shakeri*
DOI: 10.2174/1574892815666200713162304

Autophagy and Ubiquitination as Two Major Players in Colorectal Cancer: A Review on Recent Patents

Volume:15   Issue:2
Pp: 143-153
Javad Saffari-Chaleshtori, Majid Asadi-Samani, Maryam Rasouli and Sayed Mohammad Shafiee*
DOI: 10.2174/1574892815666200630103626

Recent Patents on Anti-Cancer Potential of Helenalin

Volume:15   Issue:2
Pp: 132-142
Priyanka Kriplani* and Kumar Guarve
DOI: 10.2174/1574892815666200702142601

Bortezomib – First Therapeutic Proteasome Inhibitor for Cancer Therapy: A Review of Patent Literature

Volume:15   Issue:2
Pp: 113-131
Pratik A. Vora*, Rakesh Patel and Abhay Dharamsi
DOI: 10.2174/1574892815666200401113805

SOX4 Serves an Oncogenic Role in the Tumourigenesis of Human Breast Adenocarcinoma by Promoting Cell Proliferation, Migration and Inhibiting Apoptosis

Volume:15   Issue:1
Pp: 49-58
Junhe Zhang*, Shujie Chai and Xinyu Ruan
DOI: 10.2174/1574892815666200212112119

Lentiviral-Mediated Beclin-1 Overexpression Inhibits Cell Proliferation and Induces Autophagy of Human Esophageal Carcinoma Eca109 Cell Xenograft in Nude Mice

Volume:15   Issue:1
Pp: 70-77
Junhe Zhang* and Weihua Dong
DOI: 10.2174/1574892814666191211130342