Recent Patents on Anti-Cancer Drug Discovery

Targeting Mevalonate Pathway in Cancer Treatment: Repurposing of Statins open access plus

Volume:13   Issue:2
Pp: 184-200
Federica Iannelli, Rita Lombardi, Maria R. Milone, Biagio Pucci, Simona De Rienzo, Alfredo Budillon* and Francesca Bruzzese*
DOI: 10.2174/1574892812666171129141211

PARP Inhibitors in Ovarian Cancer

Volume:13   Issue:4
Pp: 392-410
Gloria Mittica, Eleonora Ghisoni, Gaia Giannone, Sofia Genta, Massimo Aglietta, Anna Sapino and Giorgio Valabrega*
DOI: 10.2174/1574892813666180305165256

Use of human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors in Autoimmune Diseases and New Perspectives in Cancer Therapy open access plus

Volume:13   Issue:1
Pp: 86-105
Marco L. Lolli, Stefano Sainas, Agnese C. Pippione, Marta Giorgis, Donatella Boschi and Franco Dosio*
DOI: 10.2174/1574892812666171108124218

Advances in the Discovery of Anthraquinone-Based Anticancer Agents

Volume:13   Issue:2
Pp: 159-183
Alexander S. Tikhomirov*, Alexander A. Shtil and Andrey E. Shchekotikhin
DOI: 10.2174/1574892813666171206123114

The Application of lncRNAs in Cancer Treatment and Diagnosis

Volume:13   Issue:3
Pp: 292-301
Yi Zhang and Liling Tang*
DOI: 10.2174/1574892813666180226121819

Repurposing Disulfiram as An Anti-Cancer Agent: Updated Review on Literature and Patents

Volume:14   Issue:2
Pp: 113-132
Elmira Ekinci, Sagar Rohondia, Raheel Khan and Qingping P. Dou*
DOI: 10.2174/1574892814666190514104035

PARP Inhibitors in Epithelial Ovarian Cancer open access plus

Volume:13   Issue:2
Pp: 145-158
Kristin N. Taylor and Ramez N. Eskander*
DOI: 10.2174/1574892813666171204094822

Nucleic Acid Sensing Machinery: Targeting Innate Immune System for Cancer Therapy open access plus

Volume:13   Issue:1
Pp: 2-17
Sandra Iurescia*, Daniela Fioretti and Monica Rinaldi*
DOI: 10.2174/1574892812666171030163804

Anti-Oxidants as Chemopreventive Agents in Prostate Cancer: A Gap Between Preclinical and Clinical Studies

Volume:13   Issue:2
Pp: 224-239
Monireh Mohsenzadegan*, Farhad Seif, Mohammad M. Farajollahi and Majid Khoshmirsafa
DOI: 10.2174/1574892813666180213164700

Adenosine Receptor Ligands on Cancer Therapy: A Review of Patent Literature

Volume:13   Issue:1
Pp: 40-69
Joana B. Sousa, Paula Fresco, Carmen Diniz* and Jorge Goncalves
DOI: 10.2174/1574892812666171108115959

Brain Cancer: Implication to Disease, Therapeutic Strategies and Tumor Targeted Drug Delivery Approaches

Volume:13   Issue:1
Pp: 70-85
Viral Shah* and Pratiksha Kochar
DOI: 10.2174/1574892812666171129142023

Tobacco Smoking: Risk to Develop Addiction, Chronic Obstructive Pulmonary Disease, and Lung Cancer open access plus

Volume:14   Issue:1
Pp: 39-52
Alessia Santoro, Carlo Tomino, Giulia Prinzi, Palma Lamonaca, Vittorio Cardaci, Massimo Fini and Patrizia Russo*
DOI: 10.2174/1574892814666190102122848

Oral Submucous Fibrosis as an Overhealing Wound: Implications in Malignant Transformation

Volume:13   Issue:3
Pp: 272-291
Mohit Sharma, Smitha S. Shetty and Raghu Radhakrishnan*
DOI: 10.2174/1574892813666180227103147

HMGA and Cancer: A Review on Patent Literatures

Volume:14   Issue:3
Pp: 258-267
Marco De Martino, Alfredo Fusco and Francesco Esposito*
DOI: 10.2174/1574892814666190919152001

A Truncated Snail1 Transcription Factor Alters the Expression of Essential EMT Markers and Suppresses Tumor Cell Migration in a Human Lung Cancer Cell Line

Volume:14   Issue:2
Pp: 158-169
Mohammad Davoodzadeh Gholami, Reza Falak*, Sahel Heidari, Majid Khoshmirsafa, Mohammad H. Kazemi, Amir-Hassan Zarnani, Elaheh Safari, Nader Tajik and Gholam A. Kardar*
DOI: 10.2174/1574892814666190527111429

Novel Small Molecule Inhibitors of Programmed Cell Death (PD)-1, and its Ligand, PD-L1 in Cancer Immunotherapy: A Review Update of Patent Literature

Volume:14   Issue:2
Pp: 100-112
Spandana R. Kopalli, Tae-Bong Kang, Kwang-Ho Lee and Sushruta Koppula*
DOI: 10.2174/1574892813666181029142812

Tocotrienols and Cancer: From the State of the Art to Promising Novel Patents open access plus

Volume:14   Issue:1
Pp: 5-18
Fabrizio Fontana, Michela Raimondi, Monica Marzagalli, Roberta M. Moretti, Marina Montagnani Marelli and Patrizia Limonta*
DOI: 10.2174/1574892814666190116111827

Recent Progress of Marine Polypeptides as Anticancer Agents

Volume:13   Issue:4
Pp: 445-454
Lanhong Zheng, Yixin Xu, Xiukun Lin*, Zhixin Yuan, Minghua Liu, Shousong Cao, Fuming Zhang and Robert J. Linhardt
DOI: 10.2174/1574892813666180430110033

Recent Advances In Developing Novel Anti-Cancer Drugs Targeting Tumor Hypoxic and Acidic Microenvironments

Volume:13   Issue:4
Pp: 455-468
Weidong Li and Xueying Sun*
DOI: 10.2174/1574892813666180831102519

NLRP3 Inflammasome Activation Inhibitors in Inflammation-Associated Cancer Immunotherapy: An Update on the Recent Patents

Volume:13   Issue:1
Pp: 106-117
Spandana R. Kopalli , Tae-Bong Kang , Kwang-Ho Lee and Sushruta Koppula*
DOI: 10.2174/1574892812666171027102627

Cucurbitacins as Anticancer Agents: A Patent Review

Volume:14   Issue:2
Pp: 133-143
Hidayat Hussain*, Ivan R. Green, Muhammad Saleem, Khanzadi F. Khattak, Muhammad Irshad and Maroof Ali
DOI: 10.2174/1574892813666181119123035

Death-Associated Protein Kinase 1 as a Promising Drug Target in Cancer and Alzheimer’s Disease open access plus

Volume:14   Issue:2
Pp: 144-157
Dongmei Chen, Xiao Z. Zhou* and Tae H. Lee*
DOI: 10.2174/1574892814666181218170257

New Anti-Cancer Strategies in Testicular Germ Cell Tumors open access plus

Volume:14   Issue:1
Pp: 53-59
Paolo Chieffi*, Marco De Martino and Francesco Esposito
DOI: 10.2174/1574892814666190111120023

Amplified Crosstalk Between Estrogen Binding and GFR Signaling Mediated Pathways of ER Activation Drives Responses in Tumors Treated with Endocrine Disruptors open access plus

Volume:13   Issue:4
Pp: 428-444
Zsuzsanna Suba*
DOI: 10.2174/1574892813666180720123732

Targeting Metabolism to Counteract Tumor Angiogenesis: A Review of Patent Literature open access plus

Volume:13   Issue:4
Pp: 422-427
Sara Petrillo, Emanuela Tolosano, Luca Munaron and Tullio Genova*
DOI: 10.2174/1574892813666180528105023