Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Most Accessed Articles

Novel Drugs Targeting the SARS-CoV-2/COVID-19 Machinery promotion: free to download

Volume: 20   Issue: 16
Pp: 1423-1433
Ariane Sternberg, Dwight L. McKee and Cord Naujokat*
DOI: 10.2174/1568026620999200517043137

Akt Pathway Inhibitors

Volume: 20   Issue: 10
Pp: 883-900
Nne E. Uko, Osman F. Güner, Diane F. Matesic and J. Phillip Bowen*
DOI: 10.2174/1568026620666200224101808

Antidiabetic Potential of Naturally Occurring Sesquiterpenes: A Review

Volume: 21   Issue: 10
Pp: 851-862
Anupam Maurya*, Sweta Mohan and Subash C. Verma
DOI: 10.2174/1568026621666210305102500

Application of In silico Methods in the Design of Drugs for Neurodegenerative Diseases

Volume: 21   Issue: 11
Pp: 995-1011
Mohamad Haider, Anjali Chauhan, Sana Tariq, Dharam Pal Pathak, Nadeem Siddiqui, Soni Ali, Faheem Hyder Pottoo and Ruhi Ali*
DOI: 10.2174/1568026621666210521164545

The Role of Peroxisome Proliferator-Activated Receptor in Addiction: A Novel Drug Target

Volume: 21   Issue: 11
Pp: 964-975
Carla Quiroga, Juan José Barberena, Jocelyne Alcaraz-Silva , Sérgio Machado, Claudio Imperatori , Ali Yadollahpour , Henning Budde, Tetsuya Yamamoto, Diogo Telles-Correia and Eric Murillo-Rodríguez *
DOI: 10.2174/1568026621666210521165532

NGS-based mtDNA Profiling Could Reveal Genetic Alterations in Schizophrenia

Volume: 21   Issue: 11
Pp: 938-948
Elena Mihailova Ivanova*, Snezhina Mihailova Kandilarova, Tzvetelin Ivanov Lukanov, Elissaveta Jordanova Naumova, Katerina Valentinova Akabalieva and Vihra Krumova Milanova
DOI: 10.2174/1568026621666210521155500

The Translational Potential of Non-coding RNAs and Multimodal MRI Data Sets as Diagnostic and Differential Diagnostic Biomarkers for Mood Disorders

Volume: 21   Issue: 11
Pp: 949-963
Anna Todeva-Radneva, Katrin Aryutova, Sevdalina Kandilarova, Rositsa Paunova and Drozdstoy Stoyanov*
DOI: 10.2174/1568026621666210521144534

Does Dysbiosis Increase the Risk of Developing Schizophrenia? - A Comprehensive Narrative Review

Volume: 21   Issue: 11
Pp: 976-984
Filipa Novais*, Joana Capela, Sergio Machado, Eric Murillo-Rodriguez and Diogo Telles-Correia
DOI: 10.2174/1568026621666210521163555

Cellular Bioenergetic and Metabolic Changes in Patients with Autism Spectrum Disorder

Volume: 21   Issue: 11
Pp: 985-994
Maria Gevezova, Danail Minchev, Iliana Pacheva, Yordan Sbirkov, Ralitsa Yordanova, Elena Timova, Vasil Kotetarov, Ivan Ivanov and Victoria Sarafian*
DOI: 10.2174/1568026621666210521142131

Role of Phytomolecules in the Treatment of Obesity: Targets, Mechanisms and Limitations

Volume: 21   Issue: 10
Pp: 863-877
Shampa Ghosh, Srividya Manchala , Manchala Raghunath, Gaurav Sharma , Abhishek K. Singh* and Jitendra K. Sinha *
DOI: 10.2174/1568026621666210305101804

Development of Allosteric Modulators of Voltage-Gated Na+ Channels: A Novel Approach for an Old Target

Volume: 21   Issue: 10
Pp: 841-848
Nolan M. Dvorak, Paul A. Wadsworth, Pingyuan Wang, Jia Zhou and Fernanda Laezza*
DOI: 10.2174/1568026621666210525105359

The Bioactive Potential of Culturable Fungal Endophytes Isolated From the Leaf of Catharanthus roseus (L.) G. Don

Volume: 21   Issue: 10
Pp: 895-907
Sucheta Singh*, Surjeet Verma, Dharmendra K. Yadav, Anant Kumar, Rekha Tyagi, Priyanka Gupta, Dnyaneshwar U. Bawankule, Mahendra P. Darokar, Santosh K. Srivastava and Alok Kalra
DOI: 10.2174/1568026621666210426123437

Potential Therapeutic Relevance of CRISPR/Cas9 Guided Epigenetic Regulations for Neuropsychiatric Disorders

Volume: 21   Issue: 10
Pp: 878-894
Desh D. Singh*, Ravi Verma, Piyush Parimoo, Ashish Sahu, Vikram Kumar, Era Upadhyay and Dharmendra K. Yadav
DOI: 10.2174/1568026621666210317154502

The Effect of Recombinant Human Interferon Alpha Nasal Drops to Prevent COVID-19 Pneumonia for Medical Staff in an Epidemic Area

Volume: 21   Issue: 10
Pp: 920-927
Zhongji Meng, Tongyu Wang, Li Chen, Xinhe Chen, Longti Li, Xueqin Qin, Hai Li* and Jie Luo*
DOI: 10.2174/1568026621666210429083050

In-silico Studies and Wet-Lab Validation of Camptothecin Derivatives for Anti-Cancer Activity Against Liver (HepG2) and Lung (A549) Cancer Cell Lines

Volume: 21   Issue: 10
Pp: 908-919
Komal Kalani, Dharmendra K. Yadav, Sarfaraz Alam, Feroz Khan, Mahendra P. Kashyap, Santosh K. Srivastava* and Aditya B. Pant
DOI: 10.2174/1568026621666210426124719

An Updated Review on SARS-CoV-2 Main Proteinase (MPro): Protein Structure and Small-Molecule Inhibitors

Volume: 21   Issue: 6
Pp: 442-460
Dima A. Sabbah*, Rima Hajjo, Sanaa K. Bardaweel and Haizhen A. Zhong
DOI: 10.2174/1568026620666201207095117

Organic Antifungal Drugs and Targets of Their Action

Volume: 21   Issue: 8
Pp: 705-736
Alexander Yu Maksimov*, Svetlana Yu Balandina, Pavel A. Topanov, Irina V. Mashevskaya and Sandeep Chaudhary
DOI: 10.2174/1568026621666210108122622