Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Volume: 9 Issue: 12, August

Editorial [Hot topic: RNAi and Related Technologies: Applications in Medicinal Chemistry and Drug Discovery (Guest Editors: Keven Morris and Shelli McAlpine)]

Volume:9   Issue: 12
Pp: 1063-1064
Keven Morris and Shelli McAlpine
DOI: 10.2174/156802609789630848
Published on: 01 March, 2012

RNA Interference-Based Gene Expression Strategies Aimed at Sustained Therapeutic Inhibition of HIV

Volume:9   Issue: 12
Pp: 1065-1078
Samantha Barichievy, Sheena Saayman, Patrick Arbuthnot and Marc S. Weinberg
DOI: 10.2174/156802609789630901
Published on: 01 March, 2012

Transcriptional Regulation by Promoter Targeted RNAs open access plus

Volume:9   Issue: 12
Pp: 1079-1087
Kazuo Suzuki and Anthony D. Kelleher
DOI: 10.2174/156802609789630875
Published on: 01 March, 2012

Peptide Mediated siRNA Delivery

Volume:9   Issue: 12
Pp: 1088-1097
Mousa Jafari and P. Chen
DOI: 10.2174/156802609789630839
Published on: 01 March, 2012

Enhanced Gene Delivery and/or Efficacy by Functional Peptide and Protein

Volume:9   Issue: 12
Pp: 1098-1108
Tomoyuki Okuda, Yasuhisa Kawaguchi and Hirokazu Okamoto
DOI: 10.2174/156802609789630857
Published on: 01 March, 2012

Phosphorothioate-Stimulated Uptake of siRNA by Mammalian Cells: A Novel Route for Delivery

Volume:9   Issue: 12
Pp: 1109-1116
Anke Detzer and Georg Sczakiel
DOI: 10.2174/156802609789630884
Published on: 01 March, 2012

Systemic Delivery and Quantification of Unformulated Interfering RNAs In Vivo

Volume:9   Issue: 12
Pp: 1117-1129
Aurelie Morin, Catherine Gallou-Kabani, Jacques R.R. Mathieu and Florence Cabon
DOI: 10.2174/156802609789630820
Published on: 01 March, 2012

Lentiviral Delivery of RNAi Effectors Against HIV-1

Volume:9   Issue: 12
Pp: 1130-1143
Ying Poi Liu and Ben Berkhout
DOI: 10.2174/156802609789630866
Published on: 01 March, 2012

The Therapeutic Potential of Cell-Internalizing Aptamers

Volume:9   Issue: 12
Pp: 1144-1157
Jiehua Zhou and John J. Rossi
DOI: 10.2174/156802609789630893
Published on: 01 March, 2012