Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Volume: 7 Issue: 8, April

Editorial [Hot Topic: Phospholipase Inhibition: Medicinal Chemistry and Therapeutic Potential of PLA2 Inhibitors (Guest Editor: Dr. K.S. Rangappa)]

Volume:7   Issue: 8
Pp: 741-742
K. S. Rangappa
DOI: 10.2174/156802607780487641
Published on: 01 March, 2012

Snake Venom Phospholipase A2 Inhibitors: Medicinal Chemistry and Therapeutic Potential

Volume:7   Issue: 8
Pp: 743-756
Silvana Marcussi, Carolina D. Sant'Ana, Clayton Z. Oliveira, Aristides Quintero Rueda, Danilo L. Menaldo, Rene O. Beleboni, Rodrigo G. Stabeli, Jose R. Giglio, Marcos R. M. Fontes and Andreimar M. Soares
DOI: 10.2174/156802607780487614
Published on: 01 March, 2012

Structural Elements of Ligand Recognition Site in Secretory Phospholipase A2 and Structure-Based Design of Specific Inhibitors

Volume:7   Issue: 8
Pp: 757-764
Nagendra Singh, Rishi K. Somvanshi, Sujata Sharma, Sharmistha Dey, Punit Kaur and Tej P. Singh
DOI: 10.2174/156802607780487669
Published on: 01 March, 2012

PLA2 Mediated Arachidonate Free Radicals: PLA2 Inhibition and Neutralization of Free Radicals by Anti-Oxidants – A New Role as Anti-Inflammatory Molecule

Volume:7   Issue: 8
Pp: 765-777
B. L. Nanda, A. Nataraju, R. Rajesh, K. S. Rangappa, M. A. Shekar and B. S. Vishwanath
DOI: 10.2174/156802607780487623
Published on: 01 March, 2012

Chemistry and Structural Evaluation of Different Phospholipase A2 Inhibitors in Arachidonic Acid Pathway Mediated Inflammation and Snake Venom Toxicity

Volume:7   Issue: 8
Pp: 787-800
J. N. Narendra Sharath Chandra, K. C. Ponnappa, C. T. Sadashiva, B. S. Priya, B. L. Nanda, T. Veerabasappa Gowda, B. S. Vishwanath and K. S. Rangappa
DOI: 10.2174/156802607780487678
Published on: 01 March, 2012

Group IIA Secretory PLA2 Inhibition by Ursolic Acid: A Potent Anti-Inflammatory Molecule

Volume:7   Issue: 8
Pp: 801-809
A. Nataraj, C. D. Raghavendra Gowda, R. Rajesh and B. S. Vishwanath
DOI: 10.2174/156802607780487696
Published on: 01 March, 2012

Synthesis and Evaluation of Tricyclic Dipyrido Diazepinone Derivatives as Inhibitors of Secretory Phospholipase A2 with Anti-Inflammatory Activity

Volume:7   Issue: 8
Pp: 811-820
N. R. Thimmegowda, K. K. Dharmappa, C. S. Ananda kumar, M. P. Sadashiva, A. D. Sathish, B. L. Nanda, B. S. Vishwanath and K. S. Rangappa
DOI: 10.2174/156802607780487650
Published on: 01 March, 2012

Molecule of the Month

Volume:7   Issue: 8
Pp: 821-821
Kari Anne Myers
DOI: 10.2174/156802607780487687
Published on: 01 March, 2012