Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Volume: 7 Issue: 16, August

Editorial [Hot Topic: Fragment-Based Drug Discovery Approaches (Guest Editors: Jeffrey Albert and Judd Berman)]

Volume:7   Issue: 16
Pp: 1543-1543
Jeffrey Albert and Judd Berman
DOI: 10.2174/156802607782341127
Published on: 01 March, 2012

Fragment-Based Drug Discovery: What has it Achieved so Far?

Volume:7   Issue: 16
Pp: 1544-1567
Alexander A. Alex and Maria M. Flocco
DOI: 10.2174/156802607782341082
Published on: 01 March, 2012

The SeeDs Approach: Integrating Fragments into Drug Discovery

Volume:7   Issue: 16
Pp: 1568-1581
Roderick E. Hubbard, Ben Davis, Ijen Chen and Martin J. Drysdale
DOI: 10.2174/156802607782341109
Published on: 01 March, 2012

Fragment Based Drug Discovery Using Fluorescence Correlation Spectroscopy Techniques: Challenges and Solutions

Volume:7   Issue: 16
Pp: 1582-1591
T. Hesterkamp, J. Barker, A. Davenport and M. Whittaker
DOI: 10.2174/156802607782341064
Published on: 01 March, 2012

Practical Aspects of NMR-based Fragment Discovery

Volume:7   Issue: 16
Pp: 1592-1599
Edward R. Zartler and Huaping Mo
DOI: 10.2174/156802607782341055
Published on: 01 March, 2012

An Integrated Approach to Fragment-Based Lead Generation:Philosophy, Strategy and Case Studies from AstraZenecas Drug Discovery Programmes

Volume:7   Issue: 16
Pp: 1600-1629
Jeffrey S. Albert, Niklas Blomberg, Alexander L. Breeze, Alastair J. H. Brown, Jeremy N. Burrows, Philip D. Edwards, Rutger H. A. Folmer, Stefan Geschwindner, Ed J. Griffen, Peter W. Kenny, Thorsten Nowak, Lise-Lotte Olsson, Hitesh Sanganee and Adam B. Shapiro
DOI: 10.2174/156802607782341091
Published on: 01 March, 2012

SPR-based Fragment Screening: Advantages and Applications

Volume:7   Issue: 16
Pp: 1630-1642
T. Neumann, H-D. Junker, K. Schmidt and R. Sekul
DOI: 10.2174/156802607782341073
Published on: 01 March, 2012

Molecule of the Month

Volume:7   Issue: 16
Pp: 1643-1643
Julie D. Bolinger and Craig W. Lindsley
DOI: 10.2174/156802607782341118
Published on: 01 March, 2012