Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Volume: 7 Issue: 10, May

Editorial [Hot Topic: Small Molecule Inhibition of Protein-Protein Interaction:An Emerging Paradigm in Drug Design (Guest Editor: Craig W. Lindsley)]

Volume:7   Issue: 10
Pp: 921-921
Craig W. Lindsley
DOI: 10.2174/156802607780906780
Published on: 01 March, 2012

Protein-Protein Interaction Inhibitors: Small Molecules from Screening Techniques

Volume:7   Issue: 10
Pp: 922-927
Steven Fletcher and Andrew D. Hamilton
DOI: 10.2174/156802607780906735
Published on: 01 March, 2012

Scaffolds for Blocking Protein-Protein Interactions

Volume:7   Issue: 10
Pp: 928-942
Stefan J. Hershberger, Song-Gil Lee and Jean Chmielewski
DOI: 10.2174/156802607780906726
Published on: 01 March, 2012

Towards Drugs Targeting Multiple Proteins in a Systems Biology Approach

Volume:7   Issue: 10
Pp: 943-951
O. Keskin, A. Gursoy, B. Ma and R. Nussinov
DOI: 10.2174/156802607780906690
Published on: 01 March, 2012

Small Molecule Protein-Protein Inhibitors for the p53-MDM2 Interaction

Volume:7   Issue: 10
Pp: 952-960
Anna S. Dudkina and Craig W. Lindsley
DOI: 10.2174/156802607780906762
Published on: 01 March, 2012

Small Molecule Inhibitors of the XIAP Protein-Protein Interaction

Volume:7   Issue: 10
Pp: 966-971
Hemaka A. Rajapakse
DOI: 10.2174/156802607780906816
Published on: 01 March, 2012

Disruption of the Keap1-Containing Ubiquitination Complex as an Antioxidant Therapy

Volume:7   Issue: 10
Pp: 972-978
Jonathan T. Kern, Mark Hannink and J. Fred Hess
DOI: 10.2174/156802607780906825
Published on: 01 March, 2012

Editorial [Hot Topic: Computational Approaches in Medicinal Chemistry and Drug Discovery (Guest Editor: Dr. Fredy Sussman)]

Volume:7   Issue: 10
Pp: 979-979
Fredy Sussman
DOI: 10.2174/156802607780906834
Published on: 01 March, 2012

The Search for Drug Leads Targeted to the β -Secretase: An Example of the Roles of Computer Assisted Approaches in Drug Discovery

Volume:7   Issue: 10
Pp: 980-990
M. Carmen Villaverde, Lucia Gonzalez-Louro and Fredy Sussman
DOI: 10.2174/156802607780906708
Published on: 01 March, 2012

Structural Models of Class A G Protein-Coupled Receptors as a Tool for Drug Design: Insights on Transmembrane Bundle Plasticity

Volume:7   Issue: 10
Pp: 991-998
Xavier Deupi, Nicole Dolker, Maria Luz Lopez-Rodriguez, Mercedes Campillo, Juan A. Ballesteros and Leonardo Pardo
DOI: 10.2174/156802607780906799
Published on: 01 March, 2012

Trp/Met/Phe Hot Spots in Protein-Protein Interactions: Potential Targets in Drug Design

Volume:7   Issue: 10
Pp: 999-1005
Buyong Ma and Ruth Nussinov
DOI: 10.2174/156802607780906717
Published on: 01 March, 2012

Ligand Docking and Structure-based Virtual Screening in Drug Discovery

Volume:7   Issue: 10
Pp: 1006-1014
Claudio N. Cavasotto and Andrew J. W. Orry
DOI: 10.2174/156802607780906753
Published on: 01 March, 2012

Medicinal Chemistry and Bioinformatics - Current Trends in Drugs Discovery with Networks Topological Indices

Volume:7   Issue: 10
Pp: 1015-1029
Humberto Gonzalez-Diaz, Santiago Vilar, Lourdes Santana and Eugenio Uriarte
DOI: 10.2174/156802607780906771
Published on: 01 March, 2012

Structure Based Drug Design for HIV Protease: From Molecular Modeling to Cheminformatics

Volume:7   Issue: 10
Pp: 1030-1038
Patra Volarath, Robert W. Harrison and Irene T. Weber
DOI: 10.2174/156802607780906744
Published on: 01 March, 2012

Molecule of the Month

Volume:7   Issue: 10
Pp: 1039-1039
R. Nathan Daniels and Craig W. Lindsley
DOI: 10.2174/156802607780906807
Published on: 01 March, 2012