Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Editorial [ Purine Binding Proteins as Anti-Cancer Targets Guest Editor: Dr. Zhenhai Gao ] promotion: free to download

Volume:6   Issue: 11
Pp: 1069-1069
Zhenhai Gao
DOI: 10.2174/156802606777811988

Recent Advances in the Research and Development of RAF Kinase Inhibitors

Volume:6   Issue: 11
Pp: 1071-1089
Roger A. Smith, Jacques Dumas, Lila Adnane and Scott M. Wilhelm
DOI: 10.2174/156802606777812077

Inhibitors of the HSP90 Molecular Chaperone: Attacking the Master Regulator in Cancer

Volume:6   Issue: 11
Pp: 1091-1107
Edward McDonald, Paul Workman and Keith Jones
DOI: 10.2174/156802606777812004

Structure-Function Based Design of Small Molecule Inhibitors Targeting Rho Family GTPases

Volume:6   Issue: 11
Pp: 1109-1116
Nicolas Nassar, Jose Cancelas, Jie Zheng, David A. Williams and Yi Zheng
DOI: 10.2174/156802606777812095

The Purinome, a Complex Mix of Drug and Toxicity Targets

Volume:6   Issue: 11
Pp: 1117-1127
Timothy A. J.Haystead
DOI: 10.2174/156802606777812059

Targeting Cancer: The Challenges and Successes of Structure-Based Drug Design Against the Human Purinome

Volume:6   Issue: 11
Pp: 1129-1159
Mark Knapp, Cornelia Bellamacina, Jeremy M. Murray and Dirksen E. Bussiere
DOI: 10.2174/156802606777812040

Editorial [ Molecular Chaperones as Targets in Medicinal Chemistry and Drug Discovery Guest Editor: Dr. Gabriela Chiosis ] promotion: free to download

Volume:6   Issue: 11
Pp: 1161-1161
Gabriela Chiosis
DOI: 10.2174/156802606777812022

Geldanamycin, Radicicol, and Chimeric Inhibitors of the Hsp90 Nterminal ATP Binding Site

Volume:6   Issue: 11
Pp: 1173-1182
M. Kyle Hadden, Donna J. Lubbers and Brian S. J. Blagg
DOI: 10.2174/156802606777812031

Discovery and Development of Purine-Scaffold Hsp90 Inhibitors

Volume:6   Issue: 11
Pp: 1183-1191
Gabriela Chiosis
DOI: 10.2174/156802606777812013

Discovery and Development of Pyrazole-Scaffold Hsp90 Inhibitors

Volume:6   Issue: 11
Pp: 1193-1203
Edward McDonald, Keith Jones, Paul A. Brough, Martin J. Drysdale and Paul Workman
DOI: 10.2174/156802606777812086

Hsp90: A Novel Target for Cancer Therapy

Volume:6   Issue: 11
Pp: 1205-1214
David B. Solit and Neal Rosen
DOI: 10.2174/156802606777812068