Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Volume: 5 Issue: 10, September

Editorial [Hot Topic: p38 Kinase Inhibitor (Guest Editor: Katerina Leftheris)]

Volume:5   Issue: 10
Pp: 919-919
Katerina Leftheris
DOI: 10.2174/1568026054985885
Published on: 01 March, 2012

The Biology of p38 Kinase: A Central Role in Inflammation

Volume:5   Issue: 10
Pp: 921-928
Gary L. Schieven
DOI: 10.2174/1568026054985902
Published on: 01 March, 2012

Potential Adverse Effects Associated with Inhibition of p38α/β MAP Kinases

Volume:5   Issue: 10
Pp: 929-939
Donna M. Dambach
DOI: 10.2174/1568026054985911
Published on: 01 March, 2012

Discovery of Highly Selective Inhibitors of p38α

Volume:5   Issue: 10
Pp: 941-951
Ioana Popa-Burke, Steve Birkos, Leonard Blackwell, Lynn Cheatham, Jennifer Clark, John K. Dickson, Jr., Scott Galasinski, William P. Janzen, Jose Mendoza, Jennifer L. Miller, Robert P. Mohney, Paul M. Steed and C. N. Hodge
DOI: 10.2174/1568026054985867
Published on: 01 March, 2012

The Discovery of Novel Chemotypes of p38 Kinase Inhibitors

Volume:5   Issue: 10
Pp: 953-965
David J. Diller, Tsung H. Lin and Axel Metzger
DOI: 10.2174/1568026054985948
Published on: 01 March, 2012

Small Molecule p38 Inhibitors: Novel Structural Features and Advances from 2002-2005

Volume:5   Issue: 10
Pp: 967-985
John Hynes, Jr. and Katerina Leftheris
DOI: 10.2174/1568026054985920
Published on: 01 March, 2012

P38 MAP Kinase Inhibitors: Evolution of Imidazole-Based and Pyrido- Pyrimidin-2-One Lead Classes

Volume:5   Issue: 10
Pp: 987-1003
Swaminathan R. Natarajan and James B. Doherty
DOI: 10.2174/1568026054985876
Published on: 01 March, 2012

Structural Comparison of p38 Inhibitor-Protein Complexes: A Review of Recent p38 Inhibitors Having Unique Binding Interactions

Volume:5   Issue: 10
Pp: 1005-1016
Stephen T. Wrobleski and Arthur M. Doweyko
DOI: 10.2174/1568026054985894
Published on: 01 March, 2012

Pathway to the Clinic: Inhibition of P38 MAP Kinase. A Review of Ten Chemotypes Selected for Development

Volume:5   Issue: 10
Pp: 1017-1029
David M. Goldstein and Tobias Gabriel
DOI: 10.2174/1568026054985939
Published on: 01 March, 2012