Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Volume: 4 Issue: 6, February

Preface [Hot topic: Hit-to-Lead: Driving Forces for the Medicinal Chemist (Guest Editor: Benoit Deprez and Rebecca Deprez-Poulain)]

Volume:4   Issue: 6
Pp: i-i
Benoit Deprez and Rebecca Deprez-Poulain
DOI: 10.2174/1568026043451159
Published on: 01 March, 2012

Preface [Hot topic: Nicotinic Acetylcholine Receptors: Ligand Design Issues (Guest Editor: Jeffrey D. Schmitt)]

Volume:4   Issue: 6
Pp: ii-ii
Jeffrey D. Schmitt
DOI: 10.2174/1568026043451195
Published on: 01 March, 2012

Facts, Figures and Trends in Lead Generation

Volume:4   Issue: 6
Pp: 569-580
Rebecca Deprez-Poulain and Benoit Deprez
DOI: 10.2174/1568026043451168
Published on: 01 March, 2012

The Design of Screening Libraries Targeted at G-Protein Coupled Receptors

Volume:4   Issue: 6
Pp: 581-589
Roger Crossley
DOI: 10.2174/1568026043451140
Published on: 01 March, 2012

Molecular Similarity and Property Similarity

Volume:4   Issue: 6
Pp: 589-600
Frederique Barbosa and Dragos Horvath
DOI: 10.2174/1568026043451186
Published on: 01 March, 2012

Recent Developments in the Synthesis of Nicotinic Acetylcholine Receptor Ligands

Volume:4   Issue: 6
Pp: 609-629
Scott R. Breining
DOI: 10.2174/1568026043451131
Published on: 01 March, 2012

Musings on α4β2 Nicotinic Acetylcholine (nACh) Receptor Pharmacophore Models

Volume:4   Issue: 6
Pp: 631-644
Richard A. Glennon, Malgorzata Dukat and Liang Liao
DOI: 10.2174/1568026043451122
Published on: 01 March, 2012

Rational Understanding of Nicotinic Receptors Drug Binding

Volume:4   Issue: 6
Pp: 645-651
Thomas Grutter, Nicolas Le Novere and Jean-Pierre Changeux
DOI: 10.2174/1568026043451177
Published on: 01 March, 2012