Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Volume: 4 Issue: 4, February

Preface [Hot topic: Modern Aspects in the Design And Discovery of Novel Antihypertensive Drugs (Guest Editor: Thomas Mavromoustakos)]

Volume:4   Issue: 4
Pp: i-i
Thomas Mavromoustakos
DOI: 10.2174/1568026043451366
Published on: 01 March, 2012

Conformation and Bioactivity. Design and Discovery of Novel Antihypertensive Drugs

Volume:4   Issue: 4
Pp: 385-401
T. Mavromoustakos, M. Zervou, P. Zoumpoulakis, I. Kyrikou, N. P. Benetis, L. Polevaya, P. Roumelioti, N. Giatas, A. Zoga and P. Moutevelis Minakakis
DOI: 10.2174/1568026043451302
Published on: 01 March, 2012

Structural Features of Angiotensin-I Converting Enzyme Catalytic Sites: Conformational Studies in Solution, Homology Models and Comparison with Other Zinc Metallopeptidases

Volume:4   Issue: 4
Pp: 403-429
Georgios A. Spyroulias, Athanassios S. Galanis, George Pairas, Evy Manessi-Zoupa and Paul Cordopatis
DOI: 10.2174/1568026043451294
Published on: 01 March, 2012

On the Structural Basis of the Hypertensive Properties of Angiotensin II: A Solved Mystery or a Controversial Issue?

Volume:4   Issue: 4
Pp: 431-444
Andreas G. Tzakos, Ioannis P. Gerothanassis and Anastassios N. Troganis
DOI: 10.2174/1568026043451375
Published on: 01 March, 2012

Efforts to Understand the Molecular Basis of Hypertension Through Drug:Membrane Interactions

Volume:4   Issue: 4
Pp: 445-459
T. Mavromoustakos, P. Zoumpoulakis, I. Kyrikou, A. Zoga, E. Siapi, M. Zervou, I. Daliani, D. Dimitriou, A. Pitsas, C. Kamoutsis and P. Laggner
DOI: 10.2174/1568026043451339
Published on: 01 March, 2012

Simulating Physiology and Methods for Therapeutic Evaluation with Emphasis on Hypertension

Volume:4   Issue: 4
Pp: 461-471
A. K. Macpherson and S. Neti
DOI: 10.2174/1568026043451357
Published on: 01 March, 2012

Hematocrit-lowering Effect Following Inactivation of Renin-Angiotensin System with Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers

Volume:4   Issue: 4
Pp: 483-486
K. P. Marathias, B. Agroyannis, T. Mavromoustakos, J. Matsoukas and D. V. Vlahakos
DOI: 10.2174/1568026043451311
Published on: 01 March, 2012

The Shift in the “Paradigm” of the Pharmacology of Hypertension

Volume:4   Issue: 4
Pp: 487-498
Christodoulos S. Flordellis, Dimitrios Goumenos, George Kourounis, Sotirios A. Tsementzis, Herve Paris and Jaannis Vlachojiannis
DOI: 10.2174/1568026043451348
Published on: 01 March, 2012