Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Volume: 4 Issue: 3, January

Preface: Central Nicotinic Receptors and their Ligands: Setting the Scene

Volume:4   Issue: 3
Pp: ii-ii
Fulvio Gualtieri
DOI: 10.2174/15680266104040300ii
Published on: 01 March, 2012

Nicotine and Nicotinic Receptor Involvement in Neuropsychiatric Disorders

Volume:4   Issue: 3
Pp: 267-282
P. Newhouse, A. Singh and and A. Potter
DOI: 10.2174/1568026043451401
Published on: 01 March, 2012

Physiological Roles of Neuronal Nicotinic Receptors Subtypes: New Insights on the Nicotinic Modulation of Neurotransmitter Release, Synaptic Transmission and Plasticity

Volume:4   Issue: 3
Pp: 283-297
E. Sher, Y. Chen, T.J.W. Sharples, L.M. Broad, G. Benedetti, R. Zwart, G.I. McPhie, K.H. Pearson, T. Baldwinson and G. De Filippi
DOI: 10.2174/1568026043451393
Published on: 01 March, 2012

Design of Ligands for the Nicotinic Acetylcholine Receptors:The Quest for Selectivity

Volume:4   Issue: 3
Pp: 299-334
W.H. Bunnelle, Manlio M.J. Dart and M.R. Schrimpf
DOI: 10.2174/1568026043451438
Published on: 01 March, 2012

Neuronal Nicotinic Acetylcholine Receptor Agonists: Pharmacophores, Evolutionary QSAR and 3D-QSAR models

Volume:4   Issue: 3
Pp: 335-360
O. Nicolotti, C. Altomare, M. Pellegrini-Calace and A. Carotti
DOI: 10.2174/1568026043451384
Published on: 01 March, 2012

Receptor Binding Thermodynamics at the Neuronal Nicotinic Receptor

Volume:4   Issue: 3
Pp: 361-368
P.A. Borea, K. Varani, S.G., S. Merighi, A.D. Piaz, P. Gilli and G. Gilli
DOI: 10.2174/1568026043451410
Published on: 01 March, 2012

Nicotinic Acetylcholine Receptor Agonists: A Potential New Class of Analgesics

Volume:4   Issue: 3
Pp: 369-384
M.W. Decker, L.E. Rueter and R.S. Bitner
DOI: 10.2174/1568026043451447
Published on: 01 March, 2012