Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Volume: 4 Issue: 12, August

Preface [Hot Topic: Bioorganic Chemical Approaches for the Design of Protease Inhibitors (Guest Editor: Dong H. Kim)]

Volume:4   Issue: 12
Pp: i-i
Dong H. Kim
DOI: 10.2174/1568026043387872
Published on: 01 March, 2012

Preface [Hot Topic: Bioorganic Chemical Approaches for the Design of Protease Inhibitors (Guest Editor: Dong H. Kim)]

Volume:4   Issue: 12
Pp: i-i
Dong H. Kim
DOI: 10.2174/1568026043387872
Published on: 01 March, 2012

Preface [Hot Topic: Matrix Metalloproteinase Inhibitors (Guest Editor: Jeremy I. Levin)]

Volume:4   Issue: 12
Pp: ii-ii
Jeremy I. Levin
DOI: 10.2174/1568026043387926
Published on: 01 March, 2012

Preface [Hot Topic: Matrix Metalloproteinase Inhibitors (Guest Editor: Jeremy I. Levin)]

Volume:4   Issue: 12
Pp: ii-ii
Jeremy I. Levin
DOI: 10.2174/1568026043387926
Published on: 01 March, 2012

Recent Developments in the Design of Mechanism-based and Alternate Substrate Inhibitors of Serine Proteases

Volume:4   Issue: 12
Pp: 1203-1216
Jiaying Zhong and William C. Groutas
DOI: 10.2174/1568026043387971
Published on: 01 March, 2012

Chemistry-based Design of Inhibitors for Carboxypeptidase A

Volume:4   Issue: 12
Pp: 1217-1226
Dong H. Kim
DOI: 10.2174/1568026043387908
Published on: 01 March, 2012

Quest for Selectivity in Inhibition of Matrix Metalloproteinases

Volume:4   Issue: 12
Pp: 1227-1238
Stephen Brown, Samy O. Meroueh, Rafael Fridman and Shahriar Mobashery
DOI: 10.2174/1568026043387854
Published on: 01 March, 2012

Inhibitors of 3C Cysteine Proteinases from Picornaviridae

Volume:4   Issue: 12
Pp: 1239-1253
Manjinder S. Lall, Rajendra P. Jain and John C. Vederas
DOI: 10.2174/1568026043387836
Published on: 01 March, 2012

The Evolution of the Matrix Metalloproteinase Inhibitor Drug Discovery Program at Abbott Laboratories

Volume:4   Issue: 12
Pp: 1255-1267
Carol K. Wada
DOI: 10.2174/1568026043388015
Published on: 01 March, 2012

Sulfonamide-Based Acyclic and Conformationally Constrained MMP Inhibitors: From Computer-Assisted Design to Nanomolar Compounds

Volume:4   Issue: 12
Pp: 1269-1287
Stephen Hanessian and Nicolas Moitessier
DOI: 10.2174/1568026043387953
Published on: 01 March, 2012

The Design and Synthesis of Aryl Hydroxamic Acid Inhibitors of MMPs and TACE

Volume:4   Issue: 12
Pp: 1289-1310
Jeremy I. Levin
DOI: 10.2174/1568026043387935
Published on: 01 March, 2012

The Application of X-ray, NMR, and Molecular Modeling in the Design of MMP Inhibitors

Volume:4   Issue: 12
Pp: 1311-1327
Thomas S. Rush III and Robert Powers
DOI: 10.2174/1568026043387999
Published on: 01 March, 2012