Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Preface by Christopher J. Dinsmore (Hot Topic: Farnesyl-Protein Transfrase Inhibitors Guest Editor: Christopher J. Dinsmore promotion: free to download

Volume:3   Issue: 10
Pp: i-i
Christopher J. Dinsmore
DOI: 10.2174/1568026033452069

Preface by Guo Zhu Zheng promotion: free to download

Volume:3   Issue: 10
Pp: ii-ii
Guo Zhu Zheng
DOI: 10.2174/1568026033452041

Use of Synthetic Isoprenoid Analogues for Understanding Protein Prenyltransferase Mechanism and Structure

Volume:3   Issue: 10
Pp: 1043-1074
Tamara A. Kale, Shih-an J. Hsieh, Matt W. Rose and Mark D. Distefano
DOI: 10.2174/1568026033452087

Farnesyl Protein Transferase Inhibitor ZARNESTRA™ R115777 - History of a Discovery

Volume:3   Issue: 10
Pp: 1095-1102
Marc Venet, David End and Patrick Angibaud
DOI: 10.2174/1568026033452050

The Role of Absorption, Distribution, Metabolism, Excretion and Toxicity in Drug Discovery

Volume:3   Issue: 10
Pp: 1125-1154
Jing Lin, Diana C. Sahakian, Sonia M. F. de Morais, Jinghai J. Xu, Robert J. Polzer and Steven M. Winter
DOI: 10.2174/1568026033452096

Structure-Activity Relationship Studies: M2 and CCR5 Receptor Antagonists

Volume:3   Issue: 10
Pp: 1155-1169
Craig D. Boyle and Anandan Palani
DOI: 10.2174/1568026033452032

Theoretical Property Predictions

Volume:3   Issue: 10
Pp: 1171-1192
David J. Livingstone
DOI: 10.2174/1568026033452078