Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Volume: 20 Issue: 31, December 2020

New Advances in the Medicinal Chemistry of Opioid Receptor Ligands free to download

Volume:20   Issue: 31
Pp: 2821-2821
Hideaki Fujii
DOI: 10.2174/156802662031201112091807
Published on: 11 November, 2020

The G Protein Signal-Biased Compound TRV130; Structures, Its Site of Action and Clinical Studies

Volume:20   Issue: 31
Pp: 2822-2829
Kanako Miyano, Sei Manabe, Akane Komatsu, Yuriko Fujii, Yusuke Mizobuchi, Eiko Uezono, Kaori Ohshima, Miki Nonaka, Yui Kuroda, Minoru Narita and Yasuhito Uezono*
DOI: 10.2174/1568026620999201027224229
Published on: 27 October, 2020

Naldemedine: Peripherally Acting Opioid Receptor Antagonist for Treating Opioid-induced Adverse Effects

Volume:20   Issue: 31
Pp: 2830-2842
Masanao Inagaki*, Toshiyuki Kanemasa and Takaaki Yokota
DOI: 10.2174/1568026620666200710105953
Published on: 09 July, 2020

Aiming at Ideal Therapeutics-MOPr/DOPr or MOPr-DOPr Heteromertargeting Ligand

Volume:20   Issue: 31
Pp: 2843-2851
Wakako Fujita*
DOI: 10.2174/1568026620666200423095231
Published on: 22 April, 2020

Tuning Down the Pain – An Overview of Allosteric Modulation of Opioid Receptors: Mechanisms of Modulation, Allosteric Sites, Modulator Syntheses

Volume:20   Issue: 31
Pp: 2852-2865
Damian Bartuzi*, Tomasz M. Wróbel, Agnieszka A. Kaczor and Dariusz Matosiuk
DOI: 10.2174/1568026620666200601155451
Published on: 01 June, 2020

Exploring μ-Opioid Receptor Splice Variants as a Specific Molecular Target for New Analgesics

Volume:20   Issue: 31
Pp: 2866-2877
Hirokazu Mizoguchi* and Hideaki Fujii
DOI: 10.2174/1568026620666200922113430
Published on: 22 September, 2020

Nociceptin/Orphanin FQ Peptide Receptor-Related Ligands as Novel Analgesics

Volume:20   Issue: 31
Pp: 2878-2888
Norikazu Kiguchi*, Huiping Ding, Shiroh Kishioka and Mei-Chuan Ko
DOI: 10.2174/1568026620666200508082615
Published on: 07 May, 2020

δ Opioid Receptor Inverse Agonists and their In Vivo Pharmacological Effects

Volume:20   Issue: 31
Pp: 2889-2902
Shigeto Hirayama and Hideaki Fujii*
DOI: 10.2174/1568026620666200402115654
Published on: 02 April, 2020