Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Volume: 20 Issue: 2, January 2020



New Developments in the Medicinal Chemistry Targeting Drug-Resistant Infection – Part-I free to download

Volume:20   Issue: 2
Pp: 87-88
Fernando de Carvalho da Silva, Vitor Francisco Ferreira and Luana da Silva Magalhães Forezi
DOI: 10.2174/156802662002200219090340
Published on: 18 February, 2020



Functionalization of Silver Nanoparticles Loaded with Paclitaxel-induced A549 Cells Apoptosis Through ROS-Mediated Signaling Pathways

Volume:20   Issue: 2
Pp: 89-98
Jianjun Zou , Bing Zhu and Yinghua Li *
DOI: 10.2174/1568026619666191019102219
Published on: 18 October, 2019




Novel Quinolinyl-pyrrolo[3,4-d]pyrimidine-2,5-dione Derivatives Against Chloroquine-resistant Plasmodium falciparum

Volume:20   Issue: 2
Pp: 99-110
Kamilla Rodrigues Rogerio, Cedric Stephan Graebin, Luiza Helena Pinto Domingues, Luana Santos Oliveira, Vitoria de Souza Fernandes da Silva, Claudio Tadeu Daniel-Ribeiro, Leonardo J.M. Carvalho* and Nubia Boechat*
DOI: 10.2174/1568026619666191019100711
Published on: 18 October, 2019




Agathisflavone, a Biflavonoid from Anacardium occidentale L., Inhibits Influenza Virus Neuraminidase

Volume:20   Issue: 2
Pp: 111-120
Caroline S. de Freitas, Marco E.N. Rocha, Carolina Q. Sacramento, Andressa Marttorelli, André C. Ferreira, Natasha Rocha, Andrea Cheble de Oliveira, Andre Marco de Oliveira Gomes, Patrícia Souza dos Santos, Edilene Oliveira da Silva, Josineide Pantoja da Costa, Davyson de Lima Moreira, Patrícia T. Bozza, Jerson L. Silva, Shana Priscila Coutinho Barroso and Thiago Moreno L. Souza*
DOI: 10.2174/1568026620666191219150738
Published on: 19 December, 2019




Efficient Synthesis and Antibacterial Profile of Bis(2-hydroxynaphthalene- 1,4-dione)

Volume:20   Issue: 2
Pp: 121-131
Juliana S. Novais, Aline C. Rosandiski, Carolina M. de Carvalho, Letícia S. de Saules Silva, Lais C. dos S. Velasco de Souza, Marcos V. Santana, Nathalia R.C. Martins, Helena C. Castro, Vitor F. Ferreira, Daniel T.G. Gonzaga, Gabriel O. de Resende* and Fernando de C. da Silva*
DOI: 10.2174/1568026619666191210160342
Published on: 10 December, 2019




Neuraminidase from Influenza A and B Viruses is Susceptible to the Compound 4-(4-Phenyl-1H-1,2,3-Triazol-1-yl)-2,2,6,6-Tetramethylpiperidine-1- Oxyl

Volume:20   Issue: 2
Pp: 132-139
Carolina Q. Sacramento, Alessandro Kappel Jordão, Juliana L. Abrantes, Cristiane M. Alves, Andressa Marttorelli, Natalia Fintelman-Rodrigues, Caroline S. de Freitas, Gabrielle R. de Melo, Anna Claudia Cunha, Vitor F. Ferreira and Thiago Moreno L. Souza*
DOI: 10.2174/1568026620666191227142433
Published on: 27 December, 2019




Spiro-Lactams as Novel Antimicrobial Agents

Volume:20   Issue: 2
Pp: 140-152
Américo J.S. Alves, Nuno G. Alves, Cátia C. Caratão, Margarida I.M. Esteves, Diana Fontinha, Inês Bártolo, Maria I.L. Soares, Susana M.M. Lopes, Miguel Prudêncio, Nuno Taveira and Teresa M.V.D. Pinho e Melo*
DOI: 10.2174/1568026619666191105110049
Published on: 04 November, 2019




Synthesis of Coumarin Derivatives as Versatile Scaffolds for GSK-3β Enzyme Inhibition

Volume:20   Issue: 2
Pp: 153-160
Carla S. Francisco, Clara L. Javarini, Iatahanderson de S. Barcelos , Pedro A.B. Morais, Heberth de Paula, Warley de S. Borges, Álvaro Cunha Neto and Valdemar Lacerda*
DOI: 10.2174/1568026619666191019105349
Published on: 18 October, 2019




Novel [6]-gingerol Triazole Derivatives and their Antiproliferative Potential against Tumor Cells

Volume:20   Issue: 2
Pp: 161-169
William Cezar de Lima Silva, Raphael Conti, Larissa Costa de Almeida, Pedro Alves Bezerra Morais, Keyller Bastos Borges, Valdemar Lacerda Júnior, Letícia Veras Costa-Lotufo and Warley de Souza Borges*
DOI: 10.2174/1568026620666191227125507
Published on: 27 December, 2019