Current Topics in Medicinal Chemistry


Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA

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Modulation of Protein-Protein Interactions for the Development of Effective Therapeutics - From a Joint Perspective of Experiment and Computation free to download

Volume:18   Issue: 8
Pp: 645-646
Irina Sousa Moreira and Ozge Sensoy
DOI: 10.2174/156802661808180718151704

An Update on MDMX and Dual MDM2/X Inhibitors

Volume:18   Issue: 8
Pp: 647-660
Margarida Espadinha, Valentina Barcherini, Elizabeth A. Lopes and Maria M.M. Santos*
DOI: 10.2174/1568026618666180604080119

Current Status and Future Prospects of Small–molecule Protein–protein Interaction (PPI) Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL)

Volume:18   Issue: 8
Pp: 661-673
Georgia Melagraki, Georgios Leonis, Evangelos Ntougkos, Vagelis Rinotas, Christos Papaneophytou, Thomas Mavromoustakos, George Kontopidis, Eleni Douni, George Kollias* and Antreas Afantitis*
DOI: 10.2174/1568026618666180607084430

A Structural Perspective on the Modulation of Protein-Protein Interactions with Small Molecules

Volume:18   Issue: 8
Pp: 700-713
Habibe Cansu Demirel, Tunca Dogan and Nurcan Tuncbag*
DOI: 10.2174/1568026618666180601080824

Prediction and Targeting of Interaction Interfaces in G-protein Coupled Receptor Oligomers

Volume:18   Issue: 8
Pp: 714-746
Anke C. Schiedel, Meryem Kose, Carlos Barreto, Beatriz Bueschbell, Giulia Morra, Ozge Sensoy* and Irina S. Moreira*
DOI: 10.2174/1568026618666180604082610