Current Topics in Medicinal Chemistry


Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA

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Editorial: Drug Discovery for Neglected Diseases free to download

Volume:18   Issue: 5
Pp: 313-314
Adriano D. Andricopulo and Leonardo L.G. Ferreira
DOI: 10.2174/156802661805180611112621

Ubiquitin Proteasome System as a Potential Drug Target for Malaria open access plus

Volume:18   Issue: 5
Pp: 315-320
Pedro H. Scarpelli Pereira, Chiara Curra and Celia R.S. Garcia*
DOI: 10.2174/1568026618666180427145308

Polyamines and Related Nitrogen Compounds in the Chemotherapy of Neglected Diseases Caused by Kinetoplastids

Volume:18   Issue: 5
Pp: 321-368
Juan A. Bisceglia*, Maria C. Mollo, Nadia Gruber and Liliana R. Orelli*
DOI: 10.2174/1568026618666180427151338

Modern Approaches for the Discovery of Anti-Infectious Drugs for the Treatment of Neglected Diseases

Volume:18   Issue: 5
Pp: 369-381
Carolina L. Bellera, Maria L. Sbaraglini and Alan Talevi*
DOI: 10.2174/1568026618666180509151146

Insights into Anti-Trypanosomal Agents Based on Synthetic Glycoconjugates

Volume:18   Issue: 5
Pp: 382-396
Vanessa Leiria Campo*, Marcelo Fiori Marchiori and Ivone Carvalho
DOI: 10.2174/1568026618666180509145305

Structure-Based Virtual Screening and Biochemical Evaluation for the Identification of Novel Trypanosoma brucei Aldolase Inhibitors

Volume:18   Issue: 5
Pp: 397-405
Leonardo L.G. Ferreira, Rafaela S. Ferreira, David L. Palomino and Adriano D. Andricopulo*
DOI: 10.2174/1568026618666180427150428

Identification, Characterization and Molecular Modelling Studies of Schistosoma mansoni Dihydrofolate Reductase Inhibitors: From Assay Development to Hit Identification

Volume:18   Issue: 5
Pp: 406-417
Andre Lacerda Braga Teles, Roseane R. Silva, Michelle Ko, Glaucio Monteiro Ferreira, Samuel da Rocha Pita, Gustavo Henrique Goulart Trossini, Paulo Carvalho and Marcelo Santos Castilho*
DOI: 10.2174/1568026618666180509150134

First Total Synthesis of ω-Phenyl Δ6 Fatty Acids and their Leishmanicidal and Anticancer Properties

Volume:18   Issue: 5
Pp: 418-427
Nestor M. Carballeira*, Christian Morales-Guzman, Ester Alvarez-Benedicto, Zally Torres-Martinez, Yamixa Delgado, Kai H. Griebenow, Arthur D. Tinoco, Rosa M. Reguera, Yolanda Perez-Pertejo, Ruben Carbajo-Andres and Rafael Balana-Fouce
DOI: 10.2174/1568026618666180516125056