Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Current Advances in Computational Approaches for Drug Discovery- Part II free to download

Volume:18   Issue: 27
Pp: 2267-2267
Amit K. Gupta
DOI: 10.2174/156802661827190123105909
Published on: 31 January, 2019



Identification of Drug Binding Sites and Action Mechanisms with Molecular Dynamics Simulations

Volume:18   Issue: 27
Pp: 2268-2277
Yang Wang, Cecylia Severin Lupala, Haiguang Liu* and Xubo Lin*
DOI: 10.2174/1568026619666181212102856
Published on: 31 January, 2019




Hotspot Identification on Protein Surfaces Using Probe-Based MD Simulations: Successes and Challenges

Volume:18   Issue: 27
Pp: 2278-2283
Abdallah Sayyed-Ahmad*
DOI: 10.2174/1568026619666181130120308
Published on: 31 January, 2019



Counting on Fragment Based Drug Design Approach for Drug Discovery

Volume:18   Issue: 27
Pp: 2284-2293
Aanchal Kashyap, Pankaj Kumar Singh and Om Silakari*
DOI: 10.2174/1568026619666181130134250
Published on: 31 January, 2019




Identification of Therapeutically Active Molecules against Anthrax through Structure and Ligand based Drug Design

Volume:18   Issue: 27
Pp: 2294-2312
Sisir Nandi, Mridula Saxena and Anil Kumar Saxena*
DOI: 10.2174/1568026619666181221162051
Published on: 31 January, 2019




Integrated Ligand and Structure-Based Investigation of Structural Requirements for Silent Information Regulator 1 (SIRT1) Activation

Volume:18   Issue: 27
Pp: 2313-2324
Amit K. Gupta and Sun Choi*
DOI: 10.2174/1568026619666181220111059
Published on: 31 January, 2019




New Experimental and Computational Tools for Drug Discovery: Medicinal Chemistry, Molecular Docking, and Machine Learning - Part-VI free to download

Volume:18   Issue: 27
Pp: 2325-2326
Maykel Cruz Monteagudo and Humbert González-Díaz*
DOI: 10.2174/1568026619666181130122945
Published on: 31 January, 2019



Targeting α -(1,4)-Glucosidase in Diabetes Mellitus Type 2: The Role of New Synthetic Coumarins as Potent Inhibitors

Volume:18   Issue: 27
Pp: 2327-2337
Catalina Figueroa-Benavides, Maria João Matos*, Montserrat Peñaloza-Amion, Rubén Veas, Gabriela Valenzuela-Barra, Gerald Zapata, Giovanna Delogu, Eugenio Uriarte, Lourdes Santana, Claudio Olea-Azar and Carla Delporte*
DOI: 10.2174/1568026619666181130113033
Published on: 31 January, 2019




Activity of Fenticonazole, Tioconazole and Nystatin on New World Leishmania Species

Volume:18   Issue: 27
Pp: 2338-2346
Eduardo Seiji Yamamoto, Jéssica Adriana Jesus, Adriana Bezerra-Souza, Márcia Dalastra Laurenti, Susan Pereira Ribeiro and Luiz Felipe Domingues Passero*
DOI: 10.2174/1568026619666181220114627
Published on: 31 January, 2019




Computational Identification of Chemical Compounds with Potential Activity against Leishmania amazonensis using Nonlinear Machine Learning Techniques

Volume:18   Issue: 27
Pp: 2347-2354
Juan Alberto Castillo-Garit*, Naivi Flores-Balmaseda, Orlando Álvarez, Hai Pham-The, Virginia Pérez-Doñate, Francisco Torrens and Facundo Pérez-Giménez
DOI: 10.2174/1568026619666181130121558
Published on: 31 January, 2019




An In Silico Investigation of Potential EGFR Inhibitors for the Clinical Treatment of Colorectal Cancer

Volume:18   Issue: 27
Pp: 2355-2366
Manisha Majhi, Meer Asif Ali, Akanksha Limaye, Kritika Sinha, Praveena Bairagi, Megha Chouksey, Ruchi Shukla, Nisha Kanwar, Tajamul Hussain, Anuraj Nayarisseri* and Sanjeev Kumar Singh*
DOI: 10.2174/1568026619666181129144107
Published on: 31 January, 2019




Isolation and Characterization of Nuciferoic Acid, a Novel Keto Fatty Acid with Hyaluronidase Inhibitory Activity from Cocos nucifera Linn. Endocarp

Volume:18   Issue: 27
Pp: 2367-2378
Rajeev K. Singla , Mohammed Ali, Mohammad A. Kamal and Ashok K. Dubey *
DOI: 10.2174/1568026619666181224111319
Published on: 31 January, 2019