Current Topics in Medicinal Chemistry

Editor-in-Chief

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA
(USA)

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EDITORIAL (Thematic Issue : Rexinoids) free to download

Volume:17   Issue: 6
Pp: 629-630
Carl E. Wagner, Pamela A. Marshall and Peter W. Jurutka
DOI: 10.2174/156802661706170111200835



Natural and Structure-based RXR Ligand Scaffolds and Their Functions

Volume:17   Issue: 6
Pp: 631-662
Marta Dominguez, Susana Alvarez and Angel R. de Lera
DOI: 10.2174/1568026616666160617072521




Recent Progress in the Design and Discovery of RXR Modulators Targeting Alternate Binding Sites of the Receptor

Volume:17   Issue: 6
Pp: 663-675
Ying Su, Zhiping Zeng, Ziwen Chen, Dan Xu, Weidong Zhang and Xiao-kun Zhang
DOI: 10.2174/1568026616666160617092241




Translation of a Tissue-Selective Rexinoid, UAB30, to the Clinic for Breast Cancer Prevention

Volume:17   Issue: 6
Pp: 676-695
Donald D. Muccio, Venkatram R. Atigadda, Wayne J. Brouillette, Kirby I. Bland, Helen Krontiras and Clinton J. Grubbs
DOI: 10.2174/1568026616666160617093604




Retinoid X Receptor Ligands with Anti-Type 2 Diabetic Activity

Volume:17   Issue: 6
Pp: 696-707
Ken-ichi Morishita and Hiroki Kakuta
DOI: 10.2174/1568026616666160617085545




Rexinoids as Therapeutics for Alzheimer’s Disease: Role of APOE

Volume:17   Issue: 6
Pp: 708-720
Kevin P. Koster, Conor Smith, Ana C. Valencia-Olvera, Gregory R.J. Thatcher, Leon M. Tai and Mary Jo LaDu
DOI: 10.2174/1568026616666160617090227




Rexinoids for Prevention and Treatment of Cancer: Opportunities and Challenges

Volume:17   Issue: 6
Pp: 721-730
Karen T. Liby and Michael B. Sporn
DOI: 10.2174/1568026616666160617090702




Computer Simulations of the Retinoid X Receptor: Conformational Dynamics and Allosteric Networks

Volume:17   Issue: 6
Pp: 731-741
Arjan van der Vaart, Alexander Lorkowski, Ning Ma and Geoffrey M. Gray
DOI: 10.2174/1568026616666160617084745




Retinoid X Receptor Selective Agonists and their Synthetic Methods

Volume:17   Issue: 6
Pp: 742-767
Carl E. Wagner, Peter W. Jurutka, Pamela A. Marshall and Michael C. Heck
DOI: 10.2174/1568026616666160617091559