Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

Personal Subscription
Become EABM
Become Reviewer
Call for Editor
Volume: 17 Issue: 4, February 2016

Editorial (Thematic Issue: Heterocycle and Hydrocarbon Compounds from Natural Sources in Medicinal Chemistry: From Synthesis to Computational Design in Pharmacological Applications – Part II) free to download

Volume:17   Issue: 4
Pp: 381-382
Eduardo Sobarzo-Sanchez
DOI: 10.2174/1568026616666160906142336
Published on: 06 September, 2016

Mechanisms Underlying Anti-hyperalgesic Properties of Kaempferol-3,7- di-O-α-L-rhamnopyranoside Isolated from Dryopteris cycadina

Volume:17   Issue: 4
Pp: 383-390
Mumtaz Ali, Abdur Rauf, Taibi Ben Hadda, Saud Bawazeer, Tareq Abu-Izneid, Haroon Khan, Muslim Raza, Sher Ali Khan, S. U.A. Shah, Samreen Pervez, Seema Patel and Ilkay Erdogan Orhan
DOI: 10.2174/1568026616666160824101429
Published on: 23 August, 2016

Coumarin and Derivates as Lipid Lowering Agents

Volume:17   Issue: 4
Pp: 391-398
Silvia Tejada, Miquel Martorell, Xavier Capo, Josep A. Tur, Antoni Pons and Antoni Sureda
DOI: 10.2174/1568026616666160824102322
Published on: 23 August, 2016

Evaluation of the Novel Antichagasic Activity of [1,2,3]Triazolo[1,5-a]pyridine Derivatives

Volume:17   Issue: 4
Pp: 399-411
Michel Lapier, Maria C. Zuniga-Lopez, Benjamin Aguilera-Venegas, Rosa Adam, Belen Abarca, Rafael Ballesteros, Rodrigo Lopez-Munoz, Juan Diego Maya and Claudio Olea-Azar
DOI: 10.2174/1568026616666160824103040
Published on: 23 August, 2016

Elucidation of Phosphodiesterase-1 Inhibitory Effect of Some Selected Natural Polyphenolics Using In Vitro and In Silico Methods

Volume:17   Issue: 4
Pp: 412-417
Abdur Rauf, Ilkay Erdogan Orhan, Abdulselam Ertas, Hamdi Temel, Taibi Ben Hadda, Muhammad Saleem, Muslim Raza and Haroon Khan
DOI: 10.2174/1568026616666160824103615
Published on: 23 August, 2016

Heterocyclic Amaryllidaceae Alkaloids: Biosynthesis and Pharmacological Applications

Volume:17   Issue: 4
Pp: 418-427
Tarun Hotchandani and Isabel Desgagne-Penix
DOI: 10.2174/1568026616666160824104052
Published on: 23 August, 2016

Heterocyclic Compounds: Effective α-Amylase and α-Glucosidase Inhibitors

Volume:17   Issue: 4
Pp: 428-440
Mina Saeedi, Abbas Hadjiakhondi, Seyed Mohammad Nabavi and Azadeh Manayi
DOI: 10.2174/1568026616666160824104655
Published on: 23 August, 2016

Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition

Volume:17   Issue: 4
Pp: 441-459
Rosario Randino, Ilaria Moronese, Elena Cini, Valentina Bizzarro, Marco Persico, Manuela Grimaldi, Mario Scrima, Anna Maria D`Ursi, Ettore Novellino, Eduardo Sobarzo-Sánchez, Luca Rastrelli, Caterina Fattorusso, Antonello Petrella, Manuela Rodriquez* and Maurizio Taddei
DOI: 10.2174/1568026616666160824105645
Published on: 23 August, 2016

Flavonoids and Chagas' Disease: The Story So Far!

Volume:17   Issue: 4
Pp: 460-466
Seyed Fazel Nabavi, Antoni Sureda, Maria Daglia, Morteza Izadi, Luca Rastrelli and Seyed Mohammad Nabavi
DOI: 10.2174/1568026616666160824110141
Published on: 24 August, 2016

Melatonin and Respiratory Diseases: A Review

Volume:17   Issue: 4
Pp: 467-488
Solomon Habtemariam, Maria Daglia, Antoni Sureda, Zeliha Selamoglu, Mehmet Fuat Gulhan and Seyed Mohammad Nabavi
DOI: 10.2174/1568026616666160824120338
Published on: 24 August, 2016

A Medical Approach to the Monoamine Oxidase Inhibition by Using 7Hbenzo[ e]perimidin-7-one Derivatives

Volume:17   Issue: 4
Pp: 489-497
Mitchell Bacho, Eduardo Coelho-Cerqueira, Cristian Follmer, Seyed Mohammad Nabavi, Luca Rastrelli, Eugenio Uriarte and Eduardo Sobarzo-Sanchez
DOI: 10.2174/1568026616666160824120929
Published on: 24 August, 2016

New Adamantyl Chalcones: Synthesis, Antimicrobial and Anticancer Activities

Volume:17   Issue: 4
Pp: 498-506
Aouatef Tabbi, Dahmane Tebbani, Angelamaria Caporale, Carmela Saturnino, S. F. Nabavi, Palma Giuseppe, Claudio Arra, Zerrin Canturk, Gulhan Turan-Zitouni, Hocine Merazig, Eduardo Sobarzo-Sanchez and Luca Rastrelli
DOI: 10.2174/1568026616666160824121935
Published on: 24 August, 2016