Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Editorial: Metabolomics free to download

Volume:17   Issue: 24
Pp: 2715-2715
Gary W. Caldwell
DOI: 10.2174/156802661724170828093315

Can Untargeted Metabolomics Be Utilized in Drug Discovery/Development?

Volume:17   Issue: 24
Pp: 2716-2739
Gary W. Caldwell* and Gregory C. Leo
DOI: 10.2174/1568026617666170707130032

Metabolomics Applications in Precision Medicine: An Oncological Perspective open access plus

Volume:17   Issue: 24
Pp: 2740-2751
Leonor Puchades-Carrasco and Antonio Pineda- Lucena*
DOI: 10.2174/1568026617666170707120034

Molecular Determinants of Chronic Liver Disease as Studied by NMR-Metabolomics

Volume:17   Issue: 24
Pp: 2752-2766
Nieves Embade and Oscar Millet*
DOI: 10.2174/1568026617666170707124539

Evaluation of Temporal Changes in Urine-based Metabolomic and Kidney Injury Markers to Detect Compound Induced Acute Kidney Tubular Toxicity in Beagle Dogs

Volume:17   Issue: 24
Pp: 2767-2780
M. P. Wagoner*, Y. Yang, J. E. McDuffie, M. Klapczynski, W. Buck, L Cheatham, D. Eisinger, F. Sace, K. M. Lynch , M. Sonee, J-Y. Ma, Y. Chen, K. Marshall, M. Damour , L. Stephen, Y. P. Dragan, J. Fikes, S. Snook and L. B. Kinter
DOI: 10.2174/1568026617666170713172331

LC/MS/MS Profiling of Tissue Oxysterols and its Application in Dextran Sodium Sulphate Induced Mouse Colitis Models

Volume:17   Issue: 24
Pp: 2781-2790
Jiejun Wu*, J.Eric McDuffie*, Jiao Song, Michael C. Harris, Holly Raymond, Yafei Chen, Leslie Nguyen, Steven Nguyen, Justin Kanerva, Heather M. McAllister, Xiaohu Deng, Neelakandha Mani, Changlu Liu and Siquan Sun
DOI: 10.2174/1568026617666170713165519

An In Vivo Rat α-D-glucose Stable Isotope Homeostasis Drug Discovery Screen: A Targeted Metabolomics Approach

Volume:17   Issue: 24
Pp: 2791-2804
Gary W. Caldwell* and Wensheng Lang
DOI: 10.2174/1568026617666170707130401