Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Perspectives in Medicinal Chemistry: promotion: free to download

Volume:16   Issue: 4
Pp: 381-382
Guo-Ping Zhou and Wei-Zhu Zhong
DOI: 10.2174/156802661604151014114030
Published on: 14 October, 2015



Editorial (Thematic Issue: Current Progress in the Development of Metalloprotein Inhibitors) free to download

Volume:16   Issue: 4
Pp: 383-383
Chenzhong Liao
DOI: 10.2174/1568026615999150818120217
Published on: 14 October, 2015

Metalloprotein Inhibitors for the Treatment of Human Diseases

Volume:16   Issue: 4
Pp: 384-396
Yang Yang, Xue-Qin Hu, Qing-Shan Li, Xing-Xing Zhang, Ban-Feng Ruan, Jun Xu and Chenzhong Liao
DOI: 10.2174/1568026615666150813145218
Published on: 14 October, 2015


Advances in Bacterial Methionine Aminopeptidase Inhibition

Volume:16   Issue: 4
Pp: 397-414
Travis R. Helgren, Phumvadee Wangtrakuldee, Bart L. Staker and Timothy J. Hagen
DOI: 10.2174/1568026615666150813145410
Published on: 14 October, 2015


Selective Histone Deacetylase Inhibitors with Anticancer Activity

Volume:16   Issue: 4
Pp: 415-426
Nan Ma, Ying Luo, Ying Wang, Chenzhong Liao, Wen-Cai Ye and Sheng Jiang
DOI: 10.2174/1568026615666150813145629
Published on: 14 October, 2015


Panobinostat: The Small Molecule Metalloenzyme Inhibitor with Marvelous Anticancer Activity

Volume:16   Issue: 4
Pp: 427-434
Shabir Ahmad Ganai
DOI: 10.2174/1568026615666150813145800
Published on: 14 October, 2015


6,7-Dihydroxyisoindolin-1-one and 7,8-Dihydroxy-3,4-Dihydroisoquinolin- 1(2H)-one Based HIV-1 Integrase Inhibitors

Volume:16   Issue: 4
Pp: 435-440
Xue Zhi Zhao, Mathieu Métifiot, Steven J. Smith, Kasthuraiah Maddali, Christophe Marchand, Stephen H. Hughes, Yves Pommier, Terrence R. Burke and Jr.
DOI: 10.2174/1568026615666150813150058
Published on: 14 October, 2015


Novel HIV-1 Integrase Inhibitor Development by Virtual Screening Based on QSAR Models

Volume:16   Issue: 4
Pp: 441-448
Laura Guasch, Alexey V. Zakharov, Olga A. Tarasova, Vladimir V. Poroikov, Chenzhong Liao and Marc C. Nicklaus
DOI: 10.2174/1568026615666150813150433
Published on: 14 October, 2015


Non-Zinc-Binding Inhibitors of MMP-13: GRID-Based Approaches to Rationalize the Binding Process

Volume:16   Issue: 4
Pp: 449-459
Antonella Di Pizio, Mariangela Agamennone and Paolo Tortorella
DOI: 10.2174/1568026615666150813150631
Published on: 14 October, 2015


In Vitro Inhibition of Glyoxalase І by Flavonoids: New Insights from Crystallographic Analysis

Volume:16   Issue: 4
Pp: 460-466
Hong Zhang, Jing Zhai, Liping Zhang, Cuiyun Li, Yining Zhao, Yunyun Chen, Qing Li and Xiao Peng Hu
DOI: 10.2174/1568026615666150813150944
Published on: 14 October, 2015