Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Perspectives in Medicinal Chemistry promotion: free to download

Volume:16   Issue: 25
Pp: 2725-2726
Sergey N. Mikhailov, Luciana Scotti, Rajeev K. Singla and Marcus T. Scotti
DOI: 10.2174/156802661625160816180839
Published on: 15 August, 2016



Editorial (Thematic Issue: Heat Shock Proteins in Disease – From Molecular Mechanisms to Therapeutics) free to download

Volume:16   Issue: 25
Pp: 2727-2728
Gabriela Chiosis
DOI: 10.2174/156802661625160816181132
Published on: 15 August, 2016

Targeting Allosteric Control Mechanisms in Heat Shock Protein 70 (Hsp70)

Volume:16   Issue: 25
Pp: 2729-2740
Xiaokai Li, Hao Shao, Isabelle R. Taylor and Jason E. Gestwicki
DOI: 10.2174/1568026616666160413140911
Published on: 15 August, 2016


Neurodegeneration and the Heat Shock Protein 70 Machinery: Implications for Therapeutic Development

Volume:16   Issue: 25
Pp: 2741-2752
Sarah N. Fontaine, Mackenzie D. Martin and Chad A. Dickey
DOI: 10.2174/1568026616666160413140741
Published on: 15 August, 2016


Heat Shock Protein (HSP) Drug Discovery and Development: Targeting Heat Shock Proteins in Disease

Volume:16   Issue: 25
Pp: 2753-2764
Liza Shrestha, Alexander Bolaender, Hardik J. Patel and Tony Taldone
DOI: 10.2174/1568026616666160413141911
Published on: 15 August, 2016


Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94

Volume:16   Issue: 25
Pp: 2765-2778
Ephraim A. Ansa-Addo, Jessica Thaxton, Feng Hong, Bill X. Wu, Yongliang Zhang, Caroline W. Fugle, Alessandra Metelli, Brian Riesenberg, Katelyn Williams, Daniel T. Gewirth, Gabriela Chiosis, Bei Liu and Zihai Li
DOI: 10.2174/1568026616666160413141613
Published on: 15 August, 2016


Paralog Specific Hsp90 Inhibitors – A Brief History and a Bright Future

Volume:16   Issue: 25
Pp: 2779-2791
Daniel T. Gewirth
DOI: 10.2174/1568026616666160413141154
Published on: 15 August, 2016


Targeting Hsp90 in Non-Cancerous Maladies

Volume:16   Issue: 25
Pp: 2792-2804
Mark R. Woodford, Diana M. Dunn, Joseph G. Ciciarelli, Kristin Beebe, Len Neckers and Mehdi Mollapour
DOI: 10.2174/1568026616666160413141753
Published on: 15 August, 2016


Hsp90 Inhibitors in Parasitic Nematodes: Prospects and Challenges

Volume:16   Issue: 25
Pp: 2805-2811
Eileen Devaney and Victoria Gillan
DOI: 10.2174/1568026616666160413140502
Published on: 15 August, 2016


Function and Chemotypes of Human Hsp70 Chaperones

Volume:16   Issue: 25
Pp: 2812-2828
Liza Shrestha and Jason C. Young
DOI: 10.2174/1568026616666160413142028
Published on: 15 August, 2016


Stressing Out Hsp90 in Neurotoxic Proteinopathies

Volume:16   Issue: 25
Pp: 2829-2838
Carmen Inda, Alexander Bolaender, Tai Wang, Srinivasa R. Gandu and John Koren III
DOI: 10.2174/1568026616666160413141350
Published on: 15 August, 2016