Current Topics in Medicinal Chemistry


Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA

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Editorial (Thematic Issue: Drug Reprofiling: An Alternative Path to Drug Discovery) free to download

Volume:16   Issue: 19
Pp: 2067-2068
C. S. Ramaa
DOI: 10.2174/156802661619160530204415

Computational Drug Repositioning: A Lateral Approach to Traditional Drug Discovery?

Volume:16   Issue: 19
Pp: 2069-2077
Niteshkumar U. Sahu and Prashant S. Kharkar
DOI: 10.2174/1568026616666160216153249

The Repurposing of Old Drugs or Unsuccessful Lead Compounds by in Silico Approaches: New Advances and Perspectives

Volume:16   Issue: 19
Pp: 2088-2106
Annamaria Martorana, Ugo Perricone and Antonino Lauria
DOI: 10.2174/1568026616666160216153457

Scaffold Repurposing of Old Drugs Towards New Cancer Drug Discovery

Volume:16   Issue: 19
Pp: 2107-2114
Haijun Chen, Jianlei Wu, Yu Gao, Haiying Chen and Jia Zhou
DOI: 10.2174/1568026616666160216155556

Reprofiling of Troglitazone Towards More Active and Less Toxic Derivatives: A New Hope for Cancer Treatment?

Volume:16   Issue: 19
Pp: 2115-2124
Sabine Mazerbourg, Sandra Kuntz, Isabelle Grillier-Vuissoz, Audrey Berthe, Marine Geoffroy, Stéphane Flament, Andrea Bordessa and Michel Boisbrun
DOI: 10.2174/1568026616666160216153036

Repositioning of DHFR Inhibitors

Volume:16   Issue: 19
Pp: 2125-2143
Arundhati Chandrashekhar Lele, Deepak Amarnath Mishra, Tengku Karmila Kamil, Sanjib Bhakta and Mariam Sohel Degani
DOI: 10.2174/1568026616666160216152540

Revisiting Non-Cancer Drugs for Cancer Therapy

Volume:16   Issue: 19
Pp: 2144-2155
Eun Ju Yang, Changjie Wu, Yifan Liu, Junfang Lv and Joong Sup Shim
DOI: 10.2174/1568026616666160216154441

An Insight into Drug Repositioning for the Development of Novel Anti-Cancer Drugs

Volume:16   Issue: 19
Pp: 2156-2168
Deepak Bhattarai, Sarbijt Singh, Yerin Jang, Seung Hyeon Han, Kyeong Lee and Yongseok Choi
DOI: 10.2174/1568026616666160216153618

Repurposing Drugs for Cancer Prevention

Volume:16   Issue: 19
Pp: 2169-2178
Daniel K. Lee and Eva Szabo
DOI: 10.2174/1568026616666160216154946

Irreversible LSD1 Inhibitors: Application of Tranylcypromine and Its Derivatives in Cancer Treatment

Volume:16   Issue: 19
Pp: 2179-2188
Yi C. Zheng, Bin Yu, Guo Z. Jiang, Xue J. Feng, Peng X. He, Xiao Y. Chu, Wen Zhao and Hong M. Liu
DOI: 10.2174/1568026616666160216154042

Repositioning of Drugs in Cardiometabolic Disorders: Importance and Current Scenario

Volume:16   Issue: 19
Pp: 2189-2200
Parmeshwar B. Katare and Sanjay K. Banerjee
DOI: 10.2174/1568026616666160216152138

Neglected Tropical Protozoan Diseases: Drug Repositioning as a Rational Option

Volume:16   Issue: 19
Pp: 2201-2222
María Laura Sbaraglini, María Cristina Vanrell, Carolina Leticia Bellera, Gustavo Benaim, Carolina Carrillo, Alan Talevi and Patricia Silvia Romano
DOI: 10.2174/1568026616666160216154309

Metformin - The Drug for the Treatment of Autoimmune Diseases; A New Use of a Known Anti-Diabetic Drug

Volume:16   Issue: 19
Pp: 2223-2230
Malgorzata Tomczynska, Michal Bijak and Joanna Saluk
DOI: 10.2174/1568026616666160216152324