Current Topics in Medicinal Chemistry


Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA

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Editorial (Thematic Issue: Drug Design and Discovery Targeting Ion Channels) free to download

Volume:16   Issue: 16
Pp: 1763-1763
Xin Li
DOI: 10.2174/1568026616999160408164939

HCN Channels Modulators: The Need for Selectivity open access plus

Volume:16   Issue: 16
Pp: 1764-1791
Maria Novella Romanelli, Laura Sartiani, Alessio Masi, Guido Mannaioni, Dina Manetti, Alessandro Mugelli and Elisabetta Cerbai
DOI: 10.2174/1568026616999160315130832

Implications of Dynamic Occupancy, Binding Kinetics, and Channel Gating Kinetics for hERG Blocker Safety Assessment and Mitigation

Volume:16   Issue: 16
Pp: 1792-1818
Robert A. Pearlstein, K. Andrew MacCannell, Gül Erdemli, Sarita Yeola, Gabriel Helmlinger, Qi-Ying Hu, Ramy Farid, William Egan, Steven Whitebread, Clayton Springer, Jeremy Beck, Hao-Ran Wang, Mateusz Maciejewski, Laszlo Urban and José S. Duca
DOI: 10.2174/1568026616666160315142156

Computer-Aided Drug Discovery and Design Targeting Ion Channels

Volume:16   Issue: 16
Pp: 1819-1829
Qiansen Zhang, Zhaobing Gao and Huaiyu Yang
DOI: 10.2174/1568026616666160315142346

Kv1.5 Inhibitors for Treatment of Atrial Fibrillation: A Tradeoff between Selectivity and Non-selectivity

Volume:16   Issue: 16
Pp: 1843-1854
Xiaoke Guo, Weilin Chen, Haopeng Sun and Qidong You
DOI: 10.2174/1568026616666160315142647

HCN Channel as Therapeutic Targets for Heart Failure and Pain

Volume:16   Issue: 16
Pp: 1855-1861
Ying Cao, Jianxin Pang and Pingzheng Zhou
DOI: 10.2174/1568026616666151215104058

Studies on Chloride Channels and their Modulators

Volume:16   Issue: 16
Pp: 1862-1876
Vaishali M. Patil and Satya P. Gupta
DOI: 10.2174/1568026616666151215104302