Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Editorial (Thematic Issue: Recent Advances in Potential Treatment of Diabetes and Diabetic Vascular Complications by Bioactive Natural Products and New Synthetic Compounds) free to download

Volume:15   Issue: 23
Pp: 2341-2341
Edyta Gendaszewska-Darmach
DOI: 10.2174/1568026615999150724115831
Published on: 20 August, 2015

An Overview of Recent Dipeptidyl Peptidase-IV Inhibitors: Linking their Structure and Physico-Chemical Properties with SAR, Pharmacokinetics and Toxicity

Volume:15   Issue: 23
Pp: 2342-2372
Andrija Smelcerovic, Filip Miljkovic, Ana Kolarevic, Jelena Lazarevic, Aleksandra Djordjevic, Gordana Kocic and Marko Anderluh
DOI: 10.2174/1568026615666150619142731
Published on: 20 August, 2015

Glycogen Phosphorylase as a Target for Type 2 Diabetes: Synthetic, Biochemical, Structural and Computational Evaluation of Novel N-acyl-N´-(β-D-glucopyranosyl) Urea Inhibitors

Volume:15   Issue: 23
Pp: 2373-2389
Anastassia L. Kantsadi, Vanessa Parmenopoulou, Dimitar N. Bakalov, Laura Snelgrove, George A. Stravodimos, Demetra S.M. Chatzileontiadou, Stella Manta, Angeliki Panagiotopoulou, Joseph M. Hayes, Dimitri Komiotis and Demetres D. Leonidas
DOI: 10.2174/1568026615666150619142253
Published on: 20 August, 2015

Insulin Sensitivity is Modified by a Glycogen Phosphorylase Inhibitor: Glucopyranosylidene-Spiro-Thiohydantoin in Streptozotocin-Induced Diabetic Rats

Volume:15   Issue: 23
Pp: 2390-2394
Tibor Docsa, Balazs Marics, Jozsef Nemeth, Csaba Huse, Laszlo Somsak, Pal Gergely and Barna Peitl
DOI: 10.2174/1568026615666150622091407
Published on: 20 August, 2015

Sulfur- and Acyl Chain-Dependent Influence of 2-Methoxy-Lysophosphatidylcholine Analogues on β Pancreatic Cells

Volume:15   Issue: 23
Pp: 2395-2405
Anna Drzazga, Anna Ciesielska and Edyta Gendaszewska-Darmach
DOI: 10.2174/1568026615666150619141239
Published on: 20 August, 2015

Tetracyclic Triterpenoids in Herbal Medicines and their Activities in Diabetes and its Complications

Volume:15   Issue: 23
Pp: 2406-2430
Kaiser Hamid, Ali Alqahtani, Moon-Sun Kim, Jun-Lae Cho, Pei H. Cui, Chun Guang Li, Paul W. Groundwater and George Q. Li
DOI: 10.2174/1568026615666150619141940
Published on: 20 August, 2015

Antidiabetic Effect of Polyphenolic Extracts from Selected Edible Plants as α-Amylase, α -Glucosidase and PTP1B Inhibitors, and β Pancreatic Cells Cytoprotective Agents - A Comparative Study

Volume:15   Issue: 23
Pp: 2431-2444
Małgorzata Zakłos-Szyda, Iwona Majewska, Małgorzata Redzynia and Maria Koziołkiewicz
DOI: 10.2174/1568026615666150619143051
Published on: 20 August, 2015

Curcumin: A Natural Product for Diabetes and its Complications

Volume:15   Issue: 23
Pp: 2445-2455
Seyed Fazel Nabavi, Raman Thiagarajan, Luca Rastrelli, Maria Daglia, Eduardo Sobarzo-Sanchez, Heshmatollah Alinezhad and Seyed Mohammad Nabavi
DOI: 10.2174/1568026615666150619142519
Published on: 20 August, 2015

Anti-inflammatory Glycosylated Flavonoids as Therapeutic Agents for Treatment of Diabetes-Impaired Wounds

Volume:15   Issue: 23
Pp: 2456-2463
Marilena Antunes-Ricardo, Janet Gutierrez-Uribe and Sergio O. Serna-Saldivar
DOI: 10.2174/1568026615666150619141702
Published on: 20 August, 2015

Proangiogenic Properties of Nucleoside 5'-O-Phosphorothioate Analogues Under Hyperglycaemic Conditions

Volume:15   Issue: 23
Pp: 2464-2474
Edyta Węgłowska, Marcin Szustak and Edyta Gendaszewska-Darmach
DOI: 10.2174/1568026615666150619142859
Published on: 20 August, 2015