Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Volume: 15 Issue: 21, November 2015

Editorial (Thematic Issue: Current Advances in Biochemistry, Medicinal Chemistry and Drug Development Strategies for Age-Related Neurodegenerative Diseases) free to download

Volume:15   Issue: 21
Pp: 2115-2115
Sandro Arguelles-Castilla
DOI: 10.2174/1568026615999150731113537
Published on: 31 July, 2015

Longevity Pathways (mTOR, SIRT, Insulin/IGF-1) as Key Modulatory Targets on Aging and Neurodegeneration

Volume:15   Issue: 21
Pp: 2116-2138
Caio Henrique Mazucanti, Joao Victor Cabral-Costa, Andrea Rodrigues Vasconcelos, Diana Zukas Andreotti, Cristoforo Scavone and Elisa Mitiko Kawamoto
DOI: 10.2174/1568026615666150610125715
Published on: 10 June, 2015

Age-Related Neurodegeneration Prevention Through mTOR Inhibition: Potential Mechanisms and Remaining Questions

Volume:15   Issue: 21
Pp: 2139-2151
Jordan B. Jahrling and Remi-Martin Laberge
DOI: 10.2174/1568026615666150610125856
Published on: 10 June, 2015

Is the Modulation of Autophagy the Future in the Treatment of Neurodegenerative Diseases?

Volume:15   Issue: 21
Pp: 2152-2174
Rosa Ana Gonzalez-Polo, Elisa Pizarro-Estrella, Sokhna M.S. Yakhine-Diop, Mario Rodríguez-Arribas, Ruben Gomez-Sanchez, Jose M. Bravo-San Pedro and Jose M. Fuentes
DOI: 10.2174/1568026615666150610130645
Published on: 10 June, 2015

Collateral Damage: Contribution of Peripheral Inflammation to Neurodegenerative Diseases

Volume:15   Issue: 21
Pp: 2193-2210
Antonio J. Herrera, Ana M. Espinosa-Oliva, Maria J. Oliva-Martin, Alejandro Carrillo-Jimenez, Jose L. Venero and Rocio M. de Pablos
DOI: 10.2174/1568026615666150610142027
Published on: 10 June, 2015

The Role of Nicotinamide Phosphoribosyltransferase in Cerebral Ischemia

Volume:15   Issue: 21
Pp: 2211-2221
Xinzhi Chen, Shangfeng Zhao, Yang Song, Yejie Shi, Rehana K. Leak and Guodong Cao
DOI: 10.2174/1568026615666150610142234
Published on: 10 June, 2015

Neuroprotective Effects of Ginkgolide B Against Ischemic Stroke: A Review of Current Literature

Volume:15   Issue: 21
Pp: 2222-2232
Seyed Mohammad Nabavi, Solomon Habtemariam, Maria Daglia, Nady Braidy, Monica Rosa Loizzo, Rosa Tundis and Seyed Fazel Nabavi
DOI: 10.2174/1568026615666150610142647
Published on: 10 June, 2015

The Role of Uric Acid and Methyl Derivatives in the Prevention of Age-Related Neurodegenerative Disorders

Volume:15   Issue: 21
Pp: 2233-2238
Roy G. Cutler, Simonetta Camandola, Kelli F. Malott, Maria A. Edelhauser and Mark P. Mattson
DOI: 10.2174/1568026615666150610143234
Published on: 10 June, 2015

Computer Aided Drug Design Studies in the Discovery of Secondary Metabolites Targeted Against Age-Related Neurodegenerative Diseases

Volume:15   Issue: 21
Pp: 2239-2252
Luciana Scotti and Marcus Tullius Scotti
DOI: 10.2174/1568026615666150610143510
Published on: 10 June, 2015