Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Volume: 15 Issue: 14, July 2015

Graphical Abstracts:

Volume:15   Issue: 14
Pp: i-iii

DOI: 10.2174/156802661514150604144716
Published on: 04 June, 2015

Editorial (Thematic Issue: Potential Therapeutic Agents based on DNA Sequence- Selective Binding Substances) free to download

Volume:15   Issue: 14
Pp: 1291-1292
Leung Sheh and Michael J. Waring
DOI: 10.2174/1568026615666150414104747
Published on: 13 April, 2015

Therapeutic Agents Based on DNA Sequence Specific Binding

Volume:15   Issue: 14
Pp: 1293-1322
Luke Pett, John A. Hartley and Konstantinos Kiakos
DOI: 10.2174/1568026615666150413155431
Published on: 13 April, 2015

Targeting Transcription Factor Binding to DNA by Competing with DNA Binders as an Approach for Controlling Gene Expression

Volume:15   Issue: 14
Pp: 1323-1358
Mohamed Amine Bouhlel, Melanie Lambert and Marie-Helene David-Cordonnier
DOI: 10.2174/1568026615666150413154713
Published on: 13 April, 2015

Minor-Groove Binding Agents: Rational Design of Carboxamide Bond Isosteres

Volume:15   Issue: 14
Pp: 1359-1371
Chi Wi Ong and Ping Syun Yang
DOI: 10.2174/1568026615666150413155251
Published on: 13 April, 2015

Structural and Functional Diversity of Estrogen Receptor Ligands

Volume:15   Issue: 14
Pp: 1372-1384
Amjad Farooq
DOI: 10.2174/1568026615666150413154841
Published on: 13 April, 2015

DNA Recognition by a Novel Bis-Intercalator, Potent Anticancer Drug XR5944

Volume:15   Issue: 14
Pp: 1385-1397
Clement Lin and Danzhou Yang
DOI: 10.2174/1568026615666150413155608
Published on: 13 April, 2015

The Interaction of DNA-Binding Ligands with Trinucleotide-Repeat DNA: Implications for Therapy and Diagnosis of Neurological Disorders

Volume:15   Issue: 14
Pp: 1398-1408
Chung-ke Chang, Cyong-Ru Jhan and Ming-Hon Hou
DOI: 10.2174/1568026615666150413155030
Published on: 13 April, 2015

Potential Therapeutic Advantages of Doxorubicin when Activated by Formaldehyde to Function as a DNA Adduct-Forming Agent

Volume:15   Issue: 14
Pp: 1409-1422
Suzanne M. Cutts, Ada Rephaeli, Abraham Nudelman, Michal Ugarenko and Don R. Phillips
DOI: 10.2174/1568026615666150413154512
Published on: 13 April, 2015