Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Editorial: (Thematic Issue: Medicinal Chemistry of Farnesoid X Receptor (FXR) Modulators: The-State-of-the-Art) free to download

Volume:14   Issue: 19
Pp: 2127-2128
Maura Marinozzi
DOI: 10.2174/1568026614666141112104841
Published on: 24 November, 2014

Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands

Volume:14   Issue: 19
Pp: 2129-2142
Andrea Carotti, Maura Marinozzi, Chiara Custodi, Bruno Cerra, Roberto Pellicciari, Antimo Gioiello and Antonio Macchiarulo
DOI: 10.2174/1568026614666141112094058
Published on: 24 November, 2014

Knocking on FXR's Door:The "Hammerhead"-Structure Series of FXRs Agonists - Amphiphilic Isoxazoles with Potent In Vitro and In Vivo Activities

Volume:14   Issue: 19
Pp: 2143-2158
Christian Gege, Olaf Kinzel, Christoph Steeneck, Andreas Schulz and Claus Kremoser
DOI: 10.2174/1568026614666141112094430
Published on: 24 November, 2014

Bile Acid Derivatives as Ligands of the Farnesoid X Receptor: Molecular Determinants for Bile Acid Binding and Receptor Modulation

Volume:14   Issue: 19
Pp: 2159-2174
Antimo Gioiello, Bruno Cerra, Serena Mostarda, Chiara Guercini, Roberto Pellicciari and Antonio Macchiarulo
DOI: 10.2174/1568026614666141112100208
Published on: 24 November, 2014

Recent Advances in Non-Steroidal FXR Antagonists Development for Therapeutic Applications

Volume:14   Issue: 19
Pp: 2175-2187
Huang Huang, Yong Xu, Jin Zhu and Jian Li
DOI: 10.2174/1568026614666141112101840
Published on: 24 November, 2014

Medicinal Chemistry and Pharmacological Effects of Farnesoid X Receptor (FXR) Antagonists

Volume:14   Issue: 19
Pp: 2188-2205
Christina Lamers, Manfred Schubert-Zsilavecz and Daniel Merk
DOI: 10.2174/1568026614666141112103516
Published on: 24 November, 2014