Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Editorial (Thematic Issue: Allosteric Modulators of G Protein-Coupled Receptors) free to download

Volume:14   Issue: 15
Pp: 1735-1737
Gregory J. Wells
DOI: 10.2174/1568026614666140826115952
Published on: 28 September, 2014

SAR Studies on Carboxylic Acid Series M1 Selective Positive Allosteric Modulators (PAMs)

Volume:14   Issue: 15
Pp: 1738-1754
Scott D. Kuduk and Douglas C. Beshore
DOI: 10.2174/1568026614666140826120224
Published on: 28 September, 2014

Chemical Biology of mGlu4 Receptor Activation: Dogmas, Challenges, Strategies and Opportunities

Volume:14   Issue: 15
Pp: 1755-1770
Xinyan Huang, Elena Dale, Robbin M. Brodbeck and Dario Doller
DOI: 10.2174/1568026614666140902143830
Published on: 28 September, 2014

Positive Allosteric Modulators for mGluR2 Receptors: A Medicinal Chemistry Perspective

Volume:14   Issue: 15
Pp: 1771-1788
Gyorgy Szabo and Gyorgy Miklos Keseru
DOI: 10.2174/1568026614666140826120716
Published on: 28 September, 2014

SAR Studies on mGlu5 Receptor Positive Allosteric Modulators (2003- 2013)

Volume:14   Issue: 15
Pp: 1789-1841
Junliang Hao and Hui Xiong
DOI: 10.2174/1568026614666140826120419
Published on: 28 September, 2014

Allosteric Inhibition of G-Protein Coupled Receptor Oligomerization: Strategies and Challenges for Drug Development

Volume:14   Issue: 15
Pp: 1842-1863
Mattan Hurevich, Alaa Talhami, Deborah E. Shalev and Chaim Gilon
DOI: 10.2174/1568026614666140901130843
Published on: 28 September, 2014