Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Volume: 13 Issue: 7, April 2013

Editorial (Hot Topic:Designing Molecules to Cross Biological Membranes)

Volume:13   Issue: 7
Pp: 775-775
R. Scott Lokey, Jennifer Liras, Spiros Liras and Matthew P. Jacobson
DOI: 10.2174/1568026611313070001
Published on: 06 May, 2013

Intestinal Targeting of Drugs: Rational Design Approaches and Challenges open access plus

Volume:13   Issue: 7
Pp: 776-802
Kevin J. Filipski, Manthena V. Varma, Ayman F. El-Kattan, Catherine M. Ambler, Roger B. Ruggeri, Theunis C. Goosen and Kimberly O. Cameron
DOI: 10.2174/1568026611313070002
Published on: 06 May, 2013

Recent Advances Toward Improving the Bioavailability of Neuronal Nitric Oxide Synthase Inhibitors

Volume:13   Issue: 7
Pp: 803-812
He Huang and Richard B. Silverman
DOI: 10.2174/1568026611313070003
Published on: 06 May, 2013

In Silico Prediction of Brain Exposure: Drug Free Fraction, Unbound Brain to Plasma Concentration Ratio and Equilibrium Half-Life

Volume:13   Issue: 7
Pp: 813-820
Morena Spreafico and Matthew P. Jacobson
DOI: 10.2174/1568026611313070004
Published on: 06 May, 2013

Form and Function in Cyclic Peptide Natural Products: A Pharmacokinetic Perspective

Volume:13   Issue: 7
Pp: 821-836
Andrew T. Bockus, Cayla M. McEwen and R. Scott Lokey
DOI: 10.2174/1568026611313070005
Published on: 06 May, 2013

High Specificity in Response of the Sodium-Dependent Multivitamin Transporter to Derivatives of Pantothenic Acid

Volume:13   Issue: 7
Pp: 837-842
Srinivas Reddy Chirapu, Charles J. Rotter, Emily L. Miller, Manthena V. Varma, Robert L. Dow and M.G. Finn
DOI: 10.2174/1568026611313070006
Published on: 06 May, 2013

Molecular Modeling and Ligand Docking for Solute Carrier (SLC) Transporters

Volume:13   Issue: 7
Pp: 843-856
Avner Schlessinger, Natalia Khuri, Kathleen M. Giacomini and Andrej Sali
DOI: 10.2174/1568026611313070007
Published on: 06 May, 2013

Medicinal Chemistry Design Principles for Liver Targeting Through OATP Transporters open access plus

Volume:13   Issue: 7
Pp: 857-866
Meihua Tu, Alan M. Mathiowetz, Jeffrey A. Pfefferkorn, Kimberly O. Cameron, Robert L. Dow, John Litchfield, Li Di, Bo Feng and Spiros Liras
DOI: 10.2174/1568026611313070008
Published on: 06 May, 2013


Volume:13   Issue: 7
Pp: 867-867

DOI: 10.2174/1568026611313070009
Published on: 06 May, 2013