Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Volume: 13 Issue: 17, September 2013

Editorial (Thematic issue: “Alkaloids in Nature: Synthesis, Isolation and Pharmacological Applications” Part 1)

Volume:13   Issue: 17
Pp: 2097-2098
Eduardo Sobarzo-Sanchez
DOI: 10.2174/15680266113139990144
Published on: 26 August, 2013

α,β-Unsaturated Diazoketones as Versatile Building Blocks for the Synthesis of Hydroxylated Piperidines, Indolizidines and Quinolizidines

Volume:13   Issue: 17
Pp: 2099-2103
Barbara Bernardim, Leonardo D. Lordello and Antonio C.B. Burtoloso
DOI: 10.2174/15680266113139990145
Published on: 26 August, 2013

Alkaloid-Metal Based Anticancer Agents open access plus

Volume:13   Issue: 17
Pp: 2104-2115
Zhen-Feng Chen, Yan-Cheng Liu, Ke-Bin Huang and Hong Liang
DOI: 10.2174/15680266113139990146
Published on: 26 August, 2013

Structural and Mechanistic Bases of the Anticancer Activity of Natural Aporphinoid Alkaloids

Volume:13   Issue: 17
Pp: 2116-2126
Yanjuan Liu, Junxi Liu, Duolong Di, Min Li and Yan Fen
DOI: 10.2174/15680266113139990147
Published on: 26 August, 2013

Behavioral Effects of 2,3-Dihydro- and Oxoisoaporphine Derivatives in Post Stroke-Depressive Like Behavior in Male Balb/c Mice

Volume:13   Issue: 17
Pp: 2127-2133
Seyed Fazel Nabavi, Eduardo Sobarzo-Sánchez, Seyed Mohammad Nabavi, Maria Daglia, Akbar Hajizadeh Moghaddam and Andrea García Silva
DOI: 10.2174/15680266113139990148
Published on: 26 August, 2013

The Last Decade of Antinociceptive Alkaloids: Structure, Synthesis, Mechanism of Action and Prospect

Volume:13   Issue: 17
Pp: 2134-2170
Niko S. Radulovic, Polina D. Blagojevic, Pavle J. Randjelovic and Nikola M. Stojanovic
DOI: 10.2174/15680266113139990149
Published on: 26 August, 2013

Mitochondria: A Promising Target for Anticancer Alkaloids open access plus

Volume:13   Issue: 17
Pp: 2171-2183
Félix A. Urra, Miguel Cordova-Delgado, Hernan Pessoa-Mahana, Oney Ramírez-Rodríguez, Boris Weiss-Lopez, Jorge Ferreira and Ramiro Araya-Maturana
DOI: 10.2174/15680266113139990150
Published on: 26 August, 2013

Recent Developments of Chiral Induction in the Syntheses of Biologically Important Alkaloids

Volume:13   Issue: 17
Pp: 2184-2199
Radha D. Pyarasani, Amalraj John and Leonardo S. Santos
DOI: 10.2174/15680266113139990151
Published on: 26 August, 2013

Pharmaceutical Applications of the Benzylisoquinoline Alkaloids from Argemone mexicana L.

Volume:13   Issue: 17
Pp: 2200-2207
Jorge Rubio-Pina and Felipe Vazquez-Flota
DOI: 10.2174/15680266113139990152
Published on: 26 August, 2013

Cyclopamine, a Naturally Occurring Alkaloid, and Its Analogues May Find Wide Applications in Cancer Therapy

Volume:13   Issue: 17
Pp: 2208-2215
Haikuo Ma, Huan-Qiu Li and Xiaohu Zhang
DOI: 10.2174/15680266113139990153
Published on: 26 August, 2013