Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Editorial [Hot Topic:The Indolylglyoxylamide Scaffold as an Useful Tool to Obtain Anxiolytic Agents (Guest Editors: Sabrina Taliani & Federico Da Settimo )] promotion: free to download

Volume:12   Issue: 4
Pp: 236-237
Sabrina Taliani and Federico Da Settimo
DOI: 10.2174/156802612799078801

Treatment Strategies of Obsessive-Compulsive Disorder and Panic Disorder/Agoraphobia open access plus

Volume:12   Issue: 4
Pp: 238-253
Donatella Marazziti, Marina Carlini and Liliana Dell'Osso
DOI: 10.2174/1568026799078688

The GABAA-BZR Complex as Target for the Development of Anxiolytic Drugs

Volume:12   Issue: 4
Pp: 254-269
Maria Letizia Trincavelli, Eleonora Da Pozzo, Simona Daniele and Claudia Martini
DOI: 10.2174/1568026799078787

Translocator Protein as a Promising Target for Novel Anxiolytics open access plus

Volume:12   Issue: 4
Pp: 270-285
Barbara Costa, Eleonora Da Pozzo and Claudia Martini
DOI: 10.2174/156802612799078720

Medicinal Chemistry of Indolylglyoxylamide GABAA/BzR High Affinity Ligands: Identification of Novel Anxiolytic/Non Sedative Agents

Volume:12   Issue: 4
Pp: 286-311
Silvia Salerno, Federico Da Settimo, Sabrina Taliani, Francesca Simorini, Concettina La Motta, Giacomo Fornaciari and Anna Maria Marini
DOI: 10.2174/156802612799078847

Geometrically Constrained Derivatives of Indolylglyoxylamides as Ligands Binding the GABAA/BzR Complex

Volume:12   Issue: 4
Pp: 312-320
S. Sartini, M. Morelli, F. Simorini, S. Taliani, S. Salerno, A. M. Marini, F. Da Settimo and C. La Motta
DOI: 10.2174/156802612799078829

From the Pharmacophore to the Homology Model of the Benzodiazepine Receptor: The Indolyglyoxylamides Affair

Volume:12   Issue: 4
Pp: 321-332
Barbara Cosimelli, Sandro Cosconati, Luciana Marinelli, Ettore Novellino and Giovanni Greco
DOI: 10.2174/156802612799078702

Medicinal Chemistry of Indolylglyoxylamide TSPO High Affinity Ligands with Anxiolytic-Like Effects

Volume:12   Issue: 4
Pp: 333-351
Francesca Simorini, Anna Maria Marini, Sabrina Taliani, Concettina La Motta, Silvia Salerno, Isabella Pugliesi and Federico Da Settimo
DOI: 10.2174/156802612799078766

Computational Studies on Translocator Protein (TSPO) and its Ligands

Volume:12   Issue: 4
Pp: 352-359
Gabriella Ortore, Tiziano Tuccinardi and Adriano Martinelli
DOI: 10.2174/156802612799078667

Recent Developments in Potential Anxiolytic Agents Targeting GABAA/BzR Complex or the Translocator Protein (18kDa) (TSPO)

Volume:12   Issue: 4
Pp: 360-370
Caroline Nothdurfter, Rainer Rupprecht and Gerhard Rammes
DOI: 10.2174/156802612799078748