Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Volume: 12 Issue: 24, December 2013



Editorial (Hot Topic: Computer-Aided Drug Design, Synthesis and Evaluation of New Anti-Cancer Drugs) free to download

Volume:12   Issue: 24
Pp: 2703-2704
M. Natalia. D. S. Cordeiro and Alejandro Speck-Planche
DOI: 10.2174/1568026611212240001
Published on: 13 March, 2013

Classification Models for Anticancer Activity open access plus

Volume:12   Issue: 24
Pp: 2705-2726
R. Dutt and A.K. Madan
DOI: 10.2174/1568026611212240002
Published on: 13 March, 2013

Fragment-Based Optimization of Small Molecule CXCL12 Inhibitors for Antagonizing the CXCL12/CXCR4 Interaction

Volume:12   Issue: 24
Pp: 2727-2740
Joshua J. Ziarek, Yan Liu, Emmanuel Smith, Guolin Zhang, Francis C. Peterson, Jun Chen, Yongping Yu, Yu Chen, Brian F. Volkman and Rongshi Li
DOI: 10.2174/1568026611212240003
Published on: 13 March, 2013

CORAL: Classification Model for Predictions of Anti-Sarcoma Activity

Volume:12   Issue: 24
Pp: 2741-2744
A.A. Toropov, A.P. Toropova, E. Benfenati, G. Gini, D. Leszczynska and J. Leszczynski
DOI: 10.2174/1568026611212240004
Published on: 13 March, 2013

Abelson Tyrosine-Protein Kinase 1 as Principal Target for Drug Discovery Against Leukemias. Role of the Current Computer-Aided Drug Design Methodologies

Volume:12   Issue: 24
Pp: 2745-2762
Alejandro Speck-Planche, Feng Luan and M.N.D.S. Cordeiro
DOI: 10.2174/1568026611212240005
Published on: 13 March, 2013

Biologically Active 4-Thiazolidinones: A Review of QSAR Studies and QSAR Modeling of Antitumor Activity

Volume:12   Issue: 24
Pp: 2763-2784
Oleh Devinyak, Borys Zimenkovsky and Roman Lesyk
DOI: 10.2174/1568026611212240006
Published on: 13 March, 2013

SAR, QSAR and Docking of Anticancer Flavonoids and Variants: A Review

Volume:12   Issue: 24
Pp: 2785-2809
Luciana Scotti, Francisco Jaime Bezerra Mendonca Junior, Diogo Rodrigo Magalhaes Moreira, Marcelo Sobral da Silva, Ivan R. Pitta and Marcus Tullius Scotti
DOI: 10.2174/1568026611212240007
Published on: 13 March, 2013

Advancement Towards Tin-based Anticancer Chemotherapeutics: Structural Modification and Computer Modeling Approach to Drug-Enzyme Interactions

Volume:12   Issue: 24
Pp: 2810-2826
Tushar S. Basu Baul, Dhrubajyoti Dutta, Dick de Vos, Herbert Hopfl, Pooja and Palwinder Singh
DOI: 10.2174/1568026611212240008
Published on: 13 March, 2013

Radical Scavengers as Ribonucleotide Reductase Inhibitors

Volume:12   Issue: 24
Pp: 2827-2842
Arijit Basu and Barij Nayan Sinha
DOI: 10.2174/1568026611212240009
Published on: 13 March, 2013

Computational Tools in the Discovery of New G-Quadruplex Ligands with Potential Anticancer Activity open access plus

Volume:12   Issue: 24
Pp: 2843-2856
Daimel Castillo-Gonzalez, Gisselle Perez-Machado, Federico Pallardo, Teresa-Maria Garrigues-Pelufo and Miguel-Angel Cabrera-Perez
DOI: 10.2174/1568026611212240010
Published on: 13 March, 2013