Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Editorial [Hot Topic: QSAR Models for Computer-Aided Drug Design and Molecular Docking for Disorders of the Central Nervous System and Other Diseases] free to download

Volume:12   Issue: 16
Pp: 1731-1733
Francisco Prado-Prado and Xerardo Garcia-Mera
DOI: 10.2174/1568026611209061731
Published on: 13 November, 2012

QSAR and Molecular Docking Techniques for the Discovery of Potent Monoamine Oxidase B Inhibitors: Computer-Aided Generation of New Rasagiline Bioisosteres open access plus

Volume:12   Issue: 16
Pp: 1734-1747
Alejandro Speck-Planche and Valeria V. Kleandrova
DOI: 10.2174/1568026611209061734
Published on: 13 November, 2012

Dipeptide Inhibitors of Thermolysin and Angiotensin I-Converting Enzyme

Volume:12   Issue: 16
Pp: 1748-1762
Mahmud Tareq Hassan Khan, Kenichi Dedachi, Toshiro Matsui, Noriyuki Kurita, Monica Borgatti, Roberto Gambari and Ingebrigt Sylte
DOI: 10.2174/1568026611209061748
Published on: 13 November, 2012

Identification of LOGP Values and Electronegativities As Structural Insights to Model Inhibitory Activity of HIV-1 Capsid Inhibitors - A SVM and MLR Aided QSAR Studies

Volume:12   Issue: 16
Pp: 1763-1774
Nishant Sharma, K.R. Ethiraj, Mukesh Yadav, Anuraj Nayarisseri S, Mona Chaurasiya, Raju Naik Vankudavath and K. Rajender Rao
DOI: 10.2174/1568026611209061763
Published on: 13 November, 2012

A Parallel Systematic-Monte Carlo Algorithm for Exploring Conformational Space open access plus

Volume:12   Issue: 16
Pp: 1790-1796
Yasset Perez-Riverol, Roberto Vera, Yuliet Mazola and Alexis Musacchio
DOI: 10.2174/1568026611209061790
Published on: 13 November, 2012

Manipulating Kynurenic Acid Levels in the Brain – On the Edge Between Neuroprotection and Cognitive Dysfunction

Volume:12   Issue: 16
Pp: 1797-1806
Levente Szalardy, Denes Zadori, Jozsef Toldi, Ferenc Fulop, Peter Klivenyi and Laszlo Vecsei
DOI: 10.2174/1568026611209061797
Published on: 13 November, 2012

Computational Approaches to Screen Candidate Ligands with Anti- Parkinson’s Activity Using R Programming

Volume:12   Issue: 16
Pp: 1807-1814
R.M. Jayadeepa and M.S. Niveditha
DOI: 10.2174/1568026611209061807
Published on: 13 November, 2012

Immunotoxicity, Flow Cytometry, and Chemoinformatics: Review, Bibliometric Analysis, and New QSAR Model of Drug Effects Over Macrophages

Volume:12   Issue: 16
Pp: 1815-1833
Esvieta Tenorio-Borroto, Claudia G. Penuelas-Rivas, Juan C. Vasquez-Chagoyan, Francisco J. Prado-Pradoa, Xerardo Garcia-Mera and Humberto Gonzalez-Diaz
DOI: 10.2174/1568026611209061815
Published on: 13 November, 2012

3D MI-DRAGON: New Model for the Reconstruction of US FDA Drug- Target Network and Theoretical-Experimental Studies of Inhibitors of Rasagiline Derivatives for AChE

Volume:12   Issue: 16
Pp: 1843-1865
Francisco Prado-Prado, Xerardo Garcia-Mera, Manuel Escobar, Nerea Alonso, Olga Caamano, Matilde Yanez and Humberto Gonzalez-Diaz
DOI: 10.2174/1568026611209061843
Published on: 13 November, 2012