Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Editorial [Hot Topic: Pharmaceutical R&D: A Knowledge-Intensive Multidisciplinary Approach (Guest Editor: Gary W. Caldwell)] promotion: free to download

Volume:12   Issue: 11
Pp: 1223-1223
Gary W. Caldwell
DOI: 10.2174/156802612800672899
Published on: 20 May, 2012

Recent Advances in Positron Emission Tomography (PET) Radiotracers for Imaging Phosphodiesterases

Volume:12   Issue: 11
Pp: 1224-1236
Jose Ignacio Andres, Meri De Angelis, Jesus Alcazar, Sofie Celen and Guy Bormans
DOI: 10.2174/156802612800672853
Published on: 20 May, 2012

An Integrated Data Management Framework for Drug Discovery – From Data Capturing to Decision Support open access plus

Volume:12   Issue: 11
Pp: 1237-1242
Walter Cedeno, Simson Alex, Edward P. Jaeger, Dimitris K. Agrafiotis and Victor S. Lobanov
DOI: 10.2174/156802612800672862
Published on: 20 May, 2012

A Novel Method for Determination of Drug Distribution in Rat Brain Tissue Sections by LC/MS/MS: Functional Tissue Microanalysis

Volume:12   Issue: 11
Pp: 1243-1249
John A. Masucci, Andrew D. Mahan, Joseph D. Kwasnoski and Gary W. Caldwell
DOI: 10.2174/156802612800672916
Published on: 20 May, 2012

Screening Strategy for Chiral and Achiral Separations in Supercritical Fluid Chromatography Mode

Volume:12   Issue: 11
Pp: 1250-1263
David Speybrouck, David Corens and Jean-Michel Argoullon
DOI: 10.2174/156802612800672907
Published on: 20 May, 2012

Chromatographic Separation of Bioactive Oxycholesterols by GC, HPLC and SFC

Volume:12   Issue: 11
Pp: 1264-1270
Heather McAllister and Jiejun Wu
DOI: 10.2174/156802612800672880
Published on: 20 May, 2012

The IC50 Concept Revisited open access plus

Volume:12   Issue: 11
Pp: 1282-1290
Gary W. Caldwell, Zhengyin Yan, Wensheng Lang and John A. Masucci
DOI: 10.2174/156802612800672844
Published on: 20 May, 2012

The Current Status of Time Dependent CYP Inhibition Assay and In Silico Drug-drug Interaction Predictions

Volume:12   Issue: 11
Pp: 1291-1297
Zhengyin Yan and Gary W. Caldwell
DOI: 10.2174/156802612800672871
Published on: 20 May, 2012

Small Molecule Compound Logistics Outsourcing – Going Beyond the “Thought Experiment”

Volume:12   Issue: 11
Pp: 1298-1308
Devon L. Ramsay, Joseph D. Kwasnoski and Gary W. Caldwell
DOI: 10.2174/156802612800672826
Published on: 20 May, 2012