Current Topics in Medicinal Chemistry

Editor-in-Chief

Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
(USA)

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Volume: 11 Issue: 7, April

Editorial [Hot topic: Effect of Stereochemistry in Medicinal Chemistry and Drug Discovery (Guest Editor: Simona Rapposelli)]

Volume:11   Issue: 7
Pp: 758-759
Simona Rapposelli
DOI: 10.2174/156802611795165179
Published on: 01 March, 2012

The Significance of Chirality in Drug Design and Development

Volume:11   Issue: 7
Pp: 760-770
W. H. Brooks, W. C. Guida and K. G. Daniel
DOI: 10.2174/156802611795165098
Published on: 01 March, 2012

Numerical Descriptors for the Characterization of Chiral Compounds and their Applications in Modeling Biological and Toxicological Activities

Volume:11   Issue: 7
Pp: 771-787
Ramanathan Natarajan and Subhash C. Basak
DOI: 10.2174/156802611795165197
Published on: 01 March, 2012

Selectivity Filters to Edit Out Deleterious Side Effects in Kinase Inhibitors

Volume:11   Issue: 7
Pp: 788-799
Sean Sessel and Ariel Fernandez
DOI: 10.2174/156802611795165089
Published on: 01 March, 2012

Chiral Kinase Inhibitors

Volume:11   Issue: 7
Pp: 800-809
Jian-kang Jiang, Min Shen, Craig J. Thomas and Mathew B. Boxer
DOI: 10.2174/156802611795165052
Published on: 01 March, 2012

Stereochemistry at the Forefront in the Design and Discovery of Novel Anti-tuberculosis Agents

Volume:11   Issue: 7
Pp: 810-818
Qingqing Huang, Rong He and Alan P. Kozikowski
DOI: 10.2174/156802611795165205
Published on: 01 March, 2012

Structural Insight Into the Crucial Role of Ligand Chirality in the Activation of PPARs by Crystallographic Methods

Volume:11   Issue: 7
Pp: 819-839
F. Loiodice and G. Pochetti
DOI: 10.2174/156802611795165106
Published on: 01 March, 2012

The Importance of Stereochemistry on the Actions of Vitamin D

Volume:11   Issue: 7
Pp: 840-859
G. Chiellini and H. F. DeLuca
DOI: 10.2174/156802611795165016
Published on: 01 March, 2012

Structural Requirements to Obtain Highly Potent and Selective 18 kDa Translocator Protein (TSPO) Ligands

Volume:11   Issue: 7
Pp: 860-886
Sabrina Taliani, Isabella Pugliesi and Federico Da Settimo
DOI: 10.2174/156802611795165142
Published on: 01 March, 2012

Glutamate Receptor Agonists: Stereochemical Aspects

Volume:11   Issue: 7
Pp: 887-906
Stine Byskov Vogensen, Jeremy R. Greenwood, Lennart Bunch and Rasmus Praetorius Clausen
DOI: 10.2174/156802611795164990
Published on: 01 March, 2012