Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Volume: 11 Issue: 23, December

Editorial [Hot Topic: The Medicinal Chemistry of Ubiquitin-Proteasome Pathway (UPP) and Its Relevance in Drug Discovery (Guest Editor: Yongqiang Zhu)]

Volume:11   Issue: 23
Pp: 2849-2849
Yongqiang Zhu
DOI: 10.2174/156802611798281339
Published on: 01 March, 2012

Proteasome Structure, Function, and Lessons Learned from Beta-Lactone Inhibitors

Volume:11   Issue: 23
Pp: 2850-2878
Michael Groll and Barbara C. Potts
DOI: 10.2174/156802611798281320
Published on: 01 March, 2012

Ubiquitination in Rho Signaling

Volume:11   Issue: 23
Pp: 2879-2887
Feng Ding, Zhenyu Yin and Hong-Rui Wang
DOI: 10.2174/156802611798281357
Published on: 01 March, 2012

Targeting the Ubiquitin-Proteasome Pathway: An Emerging Concept in Cancer Therapy

Volume:11   Issue: 23
Pp: 2888-2905
Michael Frezza, Sara Schmitt and Q. Ping Dou
DOI: 10.2174/156802611798281311
Published on: 01 March, 2012

Synthesis of Salinosporamide A and Its Analogs as 20S Proteasome Inhibitors and SAR Summarization

Volume:11   Issue: 23
Pp: 2906-2922
Yuheng Ma, Lili Qu, Zhenming Liu, Liangren Zhang, Zhenjun Yang and Lihe Zhang
DOI: 10.2174/156802611798281302
Published on: 01 March, 2012

The Immunoproteasome: An Emerging Therapeutic Target

Volume:11   Issue: 23
Pp: 2923-2930
Wooin Lee and Kyung Bo Kim
DOI: 10.2174/156802611798281348
Published on: 01 March, 2012

Progress of Computer-Aided Drug Design (CADD) of Proteasome Inhibitors

Volume:11   Issue: 23
Pp: 2931-2944
Meng Lei, Yunde Liu, Yongqiang Zhu and Zhenming Liu
DOI: 10.2174/156802611798281366
Published on: 01 March, 2012