Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Volume: 11 Issue: 22, November

Editorial [Hot Topic: The Medicinal Chemistry of Hybrid-Based Drugs Targeting Multiple Sites of Action (Guest Editors: Jose Marco-Contelles, & Elena Soriano)]

Volume:11   Issue: 22
Pp: 2714-2715
J. Marco-Contelles and E. Soriano
DOI: 10.2174/156802611798184382
Published on: 01 March, 2012

Hybrid-Based Multi-Target Ligands for the Treatment of Alzheimer's Disease

Volume:11   Issue: 22
Pp: 2716-2730
Angela Rampa, Federica Belluti, Silvia Gobbi and Alessandra Bisi
DOI: 10.2174/156802611798184409
Published on: 01 March, 2012

A Hydrazide Linker Strategy for Heterobivalent Compounds as Ortho- and Allosteric Ligands of Acetylcholine-Binding Proteins

Volume:11   Issue: 22
Pp: 2731-2748
Paul W. Elsinghorst, Wolfgang Hartig, Daniela Gundisch, Klaus Mohr, Christian Trankle and Michael Gutschow
DOI: 10.2174/156802611798184427
Published on: 01 March, 2012

Epigenetic Multiple Modulators

Volume:11   Issue: 22
Pp: 2749-2787
Rosana Alvarez, Lucia Altucci, Hinrich Gronemeyer and Angel R. de Lera
DOI: 10.2174/156802611798184436
Published on: 01 March, 2012

Lights and Shadows on Monoamine Oxidase Inhibition in Neuroprotective Pharmacological Therapies

Volume:11   Issue: 22
Pp: 2788-2796
Claudia Binda, Erika M. Milczek, Daniele Bonivento, Jin Wang, Andrea Mattevi and Dale E. Edmondson
DOI: 10.2174/156802611798184355
Published on: 01 March, 2012

Multitarget-Directed Ligands: Innovative Chemical Probes and Therapeutic Tools Against Alzheimer's Disease

Volume:11   Issue: 22
Pp: 2797-2806
Maria Laura Bolognesi, Elena Simoni, Michela Rosini, Anna Minarini, Vincenzo Tumiatti and Carlo Melchiorre
DOI: 10.2174/156802611798184373
Published on: 01 March, 2012

1,8-Naphthyridine derivatives as Cholinesterases Inhibitors and Cell Ca2+ Regulators, a Multitarget Strategy for Alzheimer's Disease

Volume:11   Issue: 22
Pp: 2807-2823
Javier Egea and Cristobal de los Rios
DOI: 10.2174/156802611798184418
Published on: 01 March, 2012

Multi-Target-Directed Ligands as Innovative Tools to Combat Trypanosomatid Diseases

Volume:11   Issue: 22
Pp: 2824-2833
Maria Laura Bolognesi
DOI: 10.2174/156802611798184391
Published on: 01 March, 2012

Multitarget Antithrombotic Drugs

Volume:11   Issue: 22
Pp: 2834-2848
Milos Ilic, Danijel Kikelj and Janez Ilas
DOI: 10.2174/156802611798184364
Published on: 01 March, 2012