Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Volume: 11 Issue: 20, October

Editorial [Hot Topic: Snakebite Management: Time For Strategic Approach (Guest Editor: K. Kemparaju)]

Volume:11   Issue: 20
Pp: 2493-2493
K. Kemparaju
DOI: 10.2174/156802611797633456
Published on: 01 March, 2012

Overlooked Issues of Snakebite Management: Time for Strategic Approach

Volume:11   Issue: 20
Pp: 2494-2508
K. S. Girish and K. Kemparaju
DOI: 10.2174/156802611797633393
Published on: 01 March, 2012

Structural and Functional Characterization of a γ-Type Phospholipase A2 Inhibitor from Bothrops jararacussu Snake Plasma

Volume:11   Issue: 20
Pp: 2509-2519
Clayton Z. Oliveira, Norival A. Santos-Filho, Danilo L. Menaldo, Johara Boldrini-Franca, Jose R. Giglio, Leonardo A. Calderon, Rodrigo G. Stabeli, Fabio H.S. Rodrigues, Ljubica Tasic, Saulo L. da Silva and Andreimar M. Soares
DOI: 10.2174/156802611797633465
Published on: 01 March, 2012

The Polyphenol 3, 4, 5 - Tri-hydroxy Benzoic Acid Inhibits Indian Daboia russelli Venom and Its Hemorrhagic Complex Induced Local Toxicity

Volume:11   Issue: 20
Pp: 2520-2530
Y. H. Mahadeswaraswamy, M. S. Kumar, Yashonandana J Gowtham, S. Nagaraju, K. S. Girish and K. Kemparaju
DOI: 10.2174/156802611797633447
Published on: 01 March, 2012

Neutralization of Local Toxicity Induced by Vipera russelli Phospholipase A2 by Lipophilic Derivative of Ascorbic Acid

Volume:11   Issue: 20
Pp: 2531-2539
Riyaz Mohamed, Holenarasipura V Shivaprasad, Noor M Jameel, Mysore A Shekar and Bannikuppe S Vishwanath
DOI: 10.2174/156802611797633429
Published on: 01 March, 2012

Therapeutic Potential of Peptides with Neutralizing Ability Towards the Venom and Toxin (CaTx-I) of Crotalus adamanteus

Volume:11   Issue: 20
Pp: 2540-2555
Ramar Perumal Samy, Maung Maung Thwin, Bradley G. Stiles, Ho Bow, Vincent T.K. Chow and Ponnampalam Gopalakrishnakone
DOI: 10.2174/156802611797633384
Published on: 01 March, 2012

Daboia russelli Venom Hyaluronidase: Purification, Characterization and Inhibition by β-3-(3-Hydroxy-4-Oxopyridyl) α-Amino-Propionic Acid

Volume:11   Issue: 20
Pp: 2556-2565
Y. H. Mahadeswaraswamy, B. Manjula, S. Devaraja, K. S. Girish and K. Kemparaju
DOI: 10.2174/156802611797633410
Published on: 01 March, 2012

Protective Effect of Schizolobium parahyba Flavonoids Against Snake Venoms and Isolated Toxins

Volume:11   Issue: 20
Pp: 2566-2577
Luis Henrique F. Vale, Mirian M. Mendes, Renata S. Fernandes, Tassia R. Costa, Lorane I. S.Hage-Melim, Maicon A. Sousa, Amelia Hamaguchi, Maria I. Homsi-Brandeburgo, Suzelei C. Franca, Carlos H. T. P. Silva, Paulo S. Pereira, Andreimar M. Soares and Veridiana M. Rodrigues
DOI: 10.2174/156802611797633438
Published on: 01 March, 2012

Characterization of Major Zinc Containing Myonecrotic and Procoagulant Metalloprotease ‘Malabarin’ from Non Lethal Trimeresurus malabaricus Snake Venom with Thrombin Like Activity: Its Neutralization by Chelating Agents

Volume:11   Issue: 20
Pp: 2578-2588
C. D. Raghavendra Gowda, H. V. Shivaprasad, R. Venkatesh Kumar, R. Rajesh, Y. K. Saikumari, B. M. Frey, F. J. Frey, B. K. Sharath and B. S. Vishwanath
DOI: 10.2174/156802611797633375
Published on: 01 March, 2012

Inhibition of Hemorrhagic Activity of Viper Venoms by N-acetyl Cysteine: Involvement of N-acetyl and Thiol Groups

Volume:11   Issue: 20
Pp: 2589-2600
K. Sunitha, M. Hemshekhar, M. Sebastin Santhosh, M. Suresh Kumar, K. Kemparaju and K. S. Girish
DOI: 10.2174/156802611797633401
Published on: 01 March, 2012