Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Editorial [Hot Topic: Methods for the Successful Application of Chemogenomics to GPCR Drug Design (Guest Editors: Stephen L. Garland & David E. Gloriam)] promotion: free to download

Volume:11   Issue: 15
Pp: 1870-1871
Stephen L. Garland and David E. Gloriam
DOI: 10.2174/156802611796391294

G Protein-Coupled Receptor Transmembrane Binding Pockets and their Applications in GPCR Research and Drug Discovery: A Survey

Volume:11   Issue: 15
Pp: 1902-1924
Nicole A. Kratochwil, Silvia Gatti-McArthur, Marius C. Hoener, Lothar Lindemann, Andreas D. Christ, Luke G. Green, Wolfgang Guba, Rainer E. Martin, Pari Malherbe, Richard H. P. Porter, Jay P. Slack, Marcel Winnig, Henrietta Dehmlow, Uwe Grether, Cornelia Hertel, Robert Narquizian, Constantinos G. Panousis, Sabine Kolczewski and Lucinda Steward
DOI: 10.2174/156802611796391267

Thematic Analysis™ : A Chemogenomic Approach to GPCR Drug Discovery

Volume:11   Issue: 15
Pp: 1925-1943
Roger Crossley, Jacqueline Anne Macritchie and Martin John Slater
DOI: 10.2174/156802611796391302

Chemogenomic Approaches for the Exploration of GPCR Space

Volume:11   Issue: 15
Pp: 1944-1955
Nathanael Weill
DOI: 10.2174/156802611796391212

Cross-Pharmacology Analysis of G Protein-Coupled Receptors

Volume:11   Issue: 15
Pp: 1956-1963
Ferran Brianso, Maria C. Carrascosa, Tudor I. Oprea and Jordi Mestres
DOI: 10.2174/156802611796391285

Chemogenomics Approaches for Receptor Deorphanization and Extensions of the Chemogenomics Concept to Phenotypic Space

Volume:11   Issue: 15
Pp: 1964-1977
Eelke van der Horst, Julio E. Peironcely, Gerard J. P. van Westen, Olaf O. van den Hoven, Warren R. J. D. Galloway, David R. Spring, Joerg K. Wegner, Herman W. T. van Vlijmen, Ad P. IJzerman, John P. Overington and Andreas Bender
DOI: 10.2174/156802611796391230

Quantitative Chemogenomics: Machine-Learning Models of Protein-Ligand Interaction

Volume:11   Issue: 15
Pp: 1978-1993
Claes R. Andersson, Mats G. Gustafsson and Helena Strombergsson
DOI: 10.2174/156802611796391249

Present Perspectives on the Automated Classification of the G-Protein Coupled Receptors (GPCRs) at the Protein Sequence Level

Volume:11   Issue: 15
Pp: 1994-2009
Matthew N. Davies, David E. Gloriam, Andrew Secker, Alex A. Freitas, Jon Timmis and Darren R. Flower
DOI: 10.2174/156802611796391221