Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Volume: 10 Issue: 5, April

Editorial [Hot Topic: The Medicinal Chemistry of Serotonin Receptor Modulators (Guest Editors: Balazs Volk and Laszlo G. Harsing, Jr.)]

Volume:10   Issue: 5
Pp: 478-478
Balazs VOLK and Laszlo G. HARSING Jr.
DOI: 10.2174/156802610791111579
Published on: 01 March, 2012

Recent Advances in the Discovery of Selective and Non-Selective 5-HT1D Receptor Ligands

Volume:10   Issue: 5
Pp: 479-492
Simon E. Ward and Jeannette M. Watson
DOI: 10.2174/156802610791111533
Published on: 01 March, 2012

Emerging Opportunities and Concerns for Drug Discovery at Serotonin 5-5-HT2B Receptors

Volume:10   Issue: 5
Pp: 493-503
Jose Brea, Julio Castro-Palomino, Sandra Yeste, Elena Cubero, Antonio Parraga, Eduardo Dominguez and Maria Isabel Loza
DOI: 10.2174/156802610791111524
Published on: 01 March, 2012

The Interactions of the 5-HT3 Receptor with Quipazine-Like Arylpiperazine Ligands. The Journey Track at the End of the First Decade of the Third Millennium

Volume:10   Issue: 5
Pp: 504-526
Andrea Cappelli, Stefania Butini, Antonella Brizzi, Sandra Gemma, Salvatore Valenti, Germano Giuliani, Maurizio Anzini, Laura Mennuni, Giuseppe Campiani, Vittorio Brizzi and Salvatore Vomero
DOI: 10.2174/156802610791111560
Published on: 01 March, 2012

Review of 5-HT4R Ligands: State of Art and Clinical Applications

Volume:10   Issue: 5
Pp: 527-553
Ronan Bureau, Michel Boulouard, Francois Dauphin, Frank Lezoualc'h and Sylvain Rault
DOI: 10.2174/156802610791111551
Published on: 01 March, 2012

Medicinal Chemistry of 5-HT5A Receptor Ligands: A Receptor Subtype with Unique Therapeutical Potential

Volume:10   Issue: 5
Pp: 554-578
Balazs Volk, Bence J. Nagy, Szilvia Vas, Diana Kostyalik, Gyula Simig and Gyorgy Bagdy
DOI: 10.2174/156802610791111588
Published on: 01 March, 2012

The Medicinal Chemistry of 5-HT6 Receptor Ligands with a Focus on Arylsulfonyltryptamine Analogs

Volume:10   Issue: 5
Pp: 579-595
Richard A. Glennon, Uma Siripurapu, Bryan L. Roth, Renata Kolanos, Mikhail L. Bondarev, Donald Sikazwe, Mase Lee and Malgorzata Dukat
DOI: 10.2174/156802610791111542
Published on: 01 March, 2012

Exploration of Structure-Activity Relationships for Dual Serotonin Transporter Reuptake Inhibitors-Histamine H3 Receptor Antagonists

Volume:10   Issue: 5
Pp: 596-616
Emily M. Stocking, Michael A. Letavic, Pascal Bonaventure and Nicholas I. Carruthers
DOI: 10.2174/156802610791111515
Published on: 01 March, 2012