Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Volume:1   Issue: 5
Pp: i-i
G. W. Caldwell
DOI: 10.2174/1568026013394903

The New Pre-Preclinical Paradigm: Compound Optimization in Early and Late Phase Drug Discovery

Volume:1   Issue: 5
Pp: 353-366
Gary W. Caldwell, David M. Ritchie, John A. Masucci, William Hageman and Zhengyin Yan
DOI: 10.2174/1568026013394949

Strategies for Absorption Screening in Drug Discovery and Development

Volume:1   Issue: 5
Pp: 367-383
Hilde Bohets, Pieter Annaert, Geert Mannens, Ludy van Beijsterveldt, Katelijne Anciaux, Peter Verboven, Willem Meuldermans and Karel Lavrijsen
DOI: 10.2174/1568026013394886

Assessing the Absorption of New Pharmaceuticals

Volume:1   Issue: 5
Pp: 385-401
Ismael J. Hidalgo
DOI: 10.2174/1568026013395010

Metabolism Profiling, and Cytochrome P450 Inhibition & Induction in Drug Discovery

Volume:1   Issue: 5
Pp: 403-425
Zhengyin Yan and Gary W. Caldwell
DOI: 10.2174/1568026013395001

Nuclear Magnetic Resonance as a Tool in Drug Discovery, Metabolism and Disposition

Volume:1   Issue: 5
Pp: 427-441
Susan Sondej Pochapsky and Thomas C. Pochapsky
DOI: 10.2174/1568026013394967

Tailoring Bioanalysis for PK Studies Supporting Drug Discovery

Volume:1   Issue: 5
Pp: 443-461
P.M.M.B.L. Timmerman, R. de Vries and B.A. Ingelse
DOI: 10.2174/1568026013394921

The Use of On-line and Off-line Chromatographic Extraction Techniques coupled with Mass Spectrometry for Support of In Vivo and In Vitro Assays in Drug Discovery

Volume:1   Issue: 5
Pp: 463-471
John A. Masucci, Gary W. Caldwell, William J. Jones, Stephen J. Juzwin, Patrick J. Sasso and Mary Evangelisto
DOI: 10.2174/1568026013394985