Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Editor's Choice

Parallelization of Molecular Docking: A Review

Volume: 18   Issue: 12
Pp: 1015-1028
Dong Dong, Zhijian Xu, Wu Zhong and Shaoliang Peng*
DOI: 10.2174/1568026618666180821145215

A Review on Plant Antimicrobials of Past Decade

Volume: 18   Issue: 10
Pp: 812-833
Preet Amol Singh, Sapna D. Desai and Jasbir Singh*
DOI: 10.2174/1568026618666180516123229

Emerging Virulence, Drug Resistance and Future Anti-fungal Drugs for Candida Pathogens

Volume: 18   Issue: 9
Pp: 759-778
Vartika Srivastava, Rajeev Kumar Singla and Ashok Kumar Dubey*
DOI: 10.2174/1568026618666180528121707

Prediction and Targeting of Interaction Interfaces in G-protein Coupled Receptor Oligomers

Volume: 18   Issue: 8
Pp: 714-746
Anke C. Schiedel, Meryem Kose, Carlos Barreto, Beatriz Bueschbell, Giulia Morra, Ozge Sensoy* and Irina S. Moreira*
DOI: 10.2174/1568026618666180604082610

Backbone-Cyclized Peptides: A Critical Review

Volume: 18   Issue: 7
Pp: 526-555
Samuel J.S. Rubin and Nir Qvit*
DOI: 10.2174/1568026618666180518092333

Polyamines and Related Nitrogen Compounds in the Chemotherapy of Neglected Diseases Caused by Kinetoplastids

Volume: 18   Issue: 5
Pp: 321-368
Juan A. Bisceglia*, Maria C. Mollo, Nadia Gruber and Liliana R. Orelli*
DOI: 10.2174/1568026618666180427151338

Current Methods Applied to Biomaterials – Characterization Approaches, Safety Assessment and Biological International Standards

Volume: 18   Issue: 4
Pp: 256-274
Justine P.R. Oliveira*, H. Ivan Melendez-Ortiz, Emilio Bucio, Patricia Terra Alves, Mayara Ingrid Sousa Lima, Luiz Ricardo Goulart, Monica B. Mathor, Gustavo H.C. Varca and Ademar B. Lugao
DOI: 10.2174/1568026618666180410151518

Aurora Kinase Inhibitors in Head and Neck Cancer

Volume: 18   Issue: 3
Pp: 199-213
Guangying Qi, Jing Liu, Sisi Mi, Takaaki Tsunematsu, Shengjian Jin, Wenhua Shao, Tian Liu, Naozumi Ishimaru, Bo Tang* and Yasusei Kudo*
DOI: 10.2174/1568026618666180112163741

Coumarin Compounds in Medicinal Chemistry: Some Important Examples from the Last Years

Volume: 18   Issue: 2
Pp: 124-148
Thiago Moreira Pereira, Daiana Portella Franco, Felipe Vitorio and Arthur Eugen Kummerle*
DOI: 10.2174/1568026618666180329115523

New Benzothiazole-based Thiazolidinones as Potent Antimicrobial Agents. Design, synthesis and Biological Evaluation

Volume: 18   Issue: 1
Pp: 75-87
Michelyne Haroun*, Christophe Tratrat, Katerina Kositzi, Evangelia Tsolaki, Anthi Petrou, Bandar Aldhubiab, Mahesh Attimarad, Sree Harsha, Athina Geronikaki*, Katharigatta N. Venugopala, Heba S. Elsewedy, Marina Sokovic, Jasna Glamoclija and Ana Ciric
DOI: 10.2174/1568026618666180206101814

The Glitter of Carbon Nanostructures in Hybrid/Composite Hydrogels for Medicinal Use

Volume: 16   Issue: 18
Pp: 1976-1989
Daniel Iglesias, Susanna Bosi, Michele Melchionna, Tatiana Da Ros and Silvia Marchesan
DOI: 10.2174/1568026616666160215154807

Resveratrol as a Potential Therapeutic Candidate for the Treatment and Management of Alzheimer's Disease

Volume: 16   Issue: 17
Pp: 1951-1960
Nady Braidy, Bat-Erdene Jugder, Anne Poljak, Tharusha Jayasena, Hussein Mansour, Seyed Mohammad Nabavi, Perminder Sachdev and Ross Grant
DOI: 10.2174/1568026616666160204121431

Implications of Dynamic Occupancy, Binding Kinetics, and Channel Gating Kinetics for hERG Blocker Safety Assessment and Mitigation

Volume: 16   Issue: 16
Pp: 1792-1818
Robert A. Pearlstein, K. Andrew MacCannell, Gül Erdemli, Sarita Yeola, Gabriel Helmlinger, Qi-Ying Hu, Ramy Farid, William Egan, Steven Whitebread, Clayton Springer, Jeremy Beck, Hao-Ran Wang, Mateusz Maciejewski, Laszlo Urban and José S. Duca
DOI: 10.2174/1568026616666160315142156

Using Genomics for Natural Product Structure Elucidation

Volume: 16   Issue: 15
Pp: 1645-1694
Jonathan I. Tietz and Douglas A. Mitchell
DOI: 10.2174/1568026616666151012111439

Electronic Nose and Exhaled Breath NMR-based Metabolomics Applications in Airways Disease

Volume: 16   Issue: 14
Pp: 1610-1630
Giuseppe Santini, Nadia Mores, Andreu Penas, Rosamaria Capuano, Chiara Mondino, Andrea Trové, Francesco Macagno, Gina Zini, Paola Cattani, Eugenio Martinelli, Andrea Motta, Giuseppe Macis, Giovanni Ciabattoni and Paolo Montuschi
DOI: 10.2174/1568026616666151223113540

Current Drug Discovery for Anti-hepatitis C Virus Targeting NS4B

Volume: 16   Issue: 12
Pp: 1362-1371
Zhenya Wang, Xinli Chen, Chunli Wu, Haiwei Xu and Hongmin Liu
DOI: 10.2174/1568026616666151120112642

Bispidine as a Privileged Scaffold

Volume: 16   Issue: 11
Pp: 1314-1342
Isabelle Tomassoli and Daniela Gündisch
DOI: 10.2174/1568026615666150915111434