Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Most Accessed Articles

Artificial Intelligence and Cheminformatics-Guided Modern Privileged Scaffold Research

Volume: 21   Issue: 28
Pp: 2593-2608
Han-Yue Qiu, Rasmus Praetorius Clausen, Yun He* and Hai-Liang Zhu*
DOI: 10.2174/1568026621666210512020434

Thiazolidinedione: A Privileged Scaffold for the Development of Anticancer Agents

Volume: 21   Issue: 28
Pp: 2529-2545
Juan Sun, Yue-Hu Chen, Han-Yu Liu, Emmerson Hondo, Yang Zhou* and Yuan-Feng Wu*
DOI: 10.2174/1568026621666210521143550

Recent Advancements in Macrolide Hybrids against Staphylococcus aureus

Volume: 21   Issue: 27
Pp: 2455-2473
Chaofan Ji and Xiaozhou Xu*
DOI: 10.2174/1568026620999201203213733

Cruzain and Rhodesain Inhibitors: Last Decade of Advances in Seeking for New Compounds Against American and African Trypanosomiases

Volume: 21   Issue: 21
Pp: 1871-1899
Igor José dos Santos Nascimento, Thiago Mendonça de Aquino and Edeildo Ferreira da Silva-Júnior*
DOI: 10.2174/1568026621666210331152702

Sterol 14α-Demethylase from Trypanosomatidae Parasites as a Promising Target for Designing New Antiparasitic Agents

Volume: 21   Issue: 21
Pp: 1900-1921
Paulo Fernando da Silva Santos-Júnior, Martine Schmitt, João Xavier de Araújo-Júnior and Edeildo Ferreira da Silva-Júnior*
DOI: 10.2174/1568026621666210303144448

Novel Drugs Targeting the SARS-CoV-2/COVID-19 Machinery promotion: free to download

Volume: 20   Issue: 16
Pp: 1423-1433
Ariane Sternberg, Dwight L. McKee and Cord Naujokat*
DOI: 10.2174/1568026620999200517043137

γ-AApeptides as a New Class of Peptidomimetics: Design, Synthesis, and Applications

Volume: 21   Issue: 28
Pp: 2574-2592
Ma Su, Yifan Zhu, Wei Wang*, Feng Liu* and Huanqiu Li *
DOI: 10.2174/1568026621666210727160852

Imidazole Scaffold Based Compounds in the Development of Therapeutic Drugs

Volume: 21   Issue: 28
Pp: 2514-2528
Fanjie Hu, Lina Zhang, Kutty Selva Nandakumar and Kui Cheng*
DOI: 10.2174/1568026621666210527103225

Transition Metal-mediated Uncaging Chemistry in Prodrug Design

Volume: 21   Issue: 24
Pp: 2205-2212
Hai Yang Shu, Ren De Zhu, Jing Wu, Xin Hua Liu and Jing Bo Shi*
DOI: 10.2174/1568026621666210624113313

Amino Acid Derived Prodrugs: An Approach to Improve the Bioavailability of Clinically Approved Drugs

Volume: 21   Issue: 24
Pp: 2170-2183
Yogesh Singh, Samriti Saklani, Tanmoy Tantra and Suresh Thareja*
DOI: 10.2174/1568026621666210602154438

Coumarins as Potential Anti-drug Resistant Cancer Agents: A Mini Review

Volume: 21   Issue: 19
Pp: 1725-1736
Gangqiang Wang, Shaofa Sun, Bin Wu and Jikai Liu*
DOI: 10.2174/1568026620999201113110041

β-Lactone Derivatives and Their Anticancer Activities: A Short Review

Volume: 21   Issue: 18
Pp: 1645-1656
Jun Wang, Yumin Shi and Dan Jiang*
DOI: 10.2174/1568026621666210402142150

Anti-breast Cancer Potential of Natural and Synthetic Coumarin Derivatives

Volume: 21   Issue: 18
Pp: 1692-1709
Feng Song, Xiankai Huo and Zeying Guo*
DOI: 10.2174/1568026621666210303145430

Contrasting Roles of the Galectin-3 in the Schizophrenia Onset, Clinical Presentation, and Somatic Comorbidity

Volume: 21   Issue: 16
Pp: 1471-1487
Milica M. Borovcanin*, Gordana D. Radosavljevic, Jelena Pantic, Jelena Milovanovic, Natasa R. Mijailovic, Aleksandar N. Arsenijevic and Nebojsa N. Arsenijevic
DOI: 10.2174/1568026621666210611162420

The Recent Development of Tetrahydro-Quinoline/Isoquinoline Based Compounds as Anticancer Agents

Volume: 21   Issue: 17
Pp: 1587-1622
Pratik Yadav, Ashish Kumar, Ismail Althagafi, Vishal Nemaysh, Reeta Rai* and Ramendra Pratap*
DOI: 10.2174/1568026621666210526164208

Larrea tridentata and its Biological Activities

Volume: 21   Issue: 26
Pp: 2352-2364
Karen Y. Reyes-Melo, Adrián A. Galván-Rodrigo, Isaí E. Martínez-Olivo, Guillermo Núñez-Mojica, Francisco G. Ávalos-Alanís, Abraham García and María del Rayo Camacho-Corona*
DOI: 10.2174/1568026621666210727170908