Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Open Access Articles

Intracellular Redox State as Target for Anti-Influenza Therapy: Are Antioxidants Always Effective? open Access plus

Volume: 14   Issue: 22
Pp: 2529-2541
Rossella Sgarbanti, Donatella Amatore, Ignacio Celestino, Maria Elena Marcocci, Alessandra Fraternale, Maria Rosa Ciriolo, Mauro Magnani, Raffaele Saladino, Enrico Garaci, Anna Teresa Palamara and Lucia Nencioni

Structure-Based Virtual Screening for Drug Discovery: Principles, Applications and Recent Advances open Access plus

Volume: 14   Issue: 16
Pp: 1923-1938
Evanthia Lionta, George Spyrou, Demetrios K. Vassilatis and Zoe Cournia

Seeding Collaborations to Advance Kinase Science with the GSK Published Kinase Inhibitor Set (PKIS) open Access plus

Volume: 14   Issue: 3
Pp: 340-342
David H. Drewry, Timothy M. Willson and William J. Zuercher

Open Innovation Drug Discovery (OIDD): A Potential Path to Novel Therapeutic Chemical Space open Access plus

Volume: 14   Issue: 3
Pp: 294-303
Maria Alvim-Gaston, Timothy Grese, Abdelaziz Mahoui, Alan D. Palkowitz, Marta Pineiro-Nunez and Ian Watson

Reviewing Colchicaceae Alkaloids – Perspectives of Evolution on Medicinal Chemistry open Access plus

Volume: 14   Issue: 2
Pp: 274-289
Sonny Larsson and Nina Ronsted

A Brief Overview of Antimicrobial Peptides Containing Unnatural Amino Acids and Ligand-Based Approaches for Peptide Ligands open Access plus

Volume: 13   Issue: 24
Pp: 3205-3224
Jayendra B. Bhonsle, Tiffany Clark, Libero Bartolotti and Rickey P. Hicks

Native Brazilian Plants Against Nosocomial Infections: A Critical Review on their Potential and the Antimicrobial Methodology open Access plus

Volume: 13   Issue: 24
Pp: 3040-3078
Paulo Roberto H. Moreno, Fabiana da Costa-Issa, Agnieszka K. Rajca-Ferreira, Marcos A. A. Pereira and Telma M. Kaneko

From Polypharmacology to Target Specificity: The Case of PARP Inhibitors open Access plus

Volume: 13   Issue: 23
Pp: 2939-2954
Paride Liscio, Emidio Camaioni, Andrea Carotti, Roberto Pellicciari and Antonio Macchiarulo

NAD Biosynthesis in Humans - Enzymes, Metabolites and Therapeutic Aspects open Access plus

Volume: 13   Issue: 23
Pp: 2907-2917
Christian Dölle, Renate Hvidsten Skoge, Magali R. VanLinden and Mathias Ziegler

Recent Advances in the Synthesis of New Antimycobacterial Agents Based on the 1H-1,2,3-Triazoles open Access plus

Volume: 13   Issue: 22
Pp: 2850-2865
Daniel Tadeu G. Gonzaga, David R. da Rocha, Fernando de C. da Silva and Vitor F. Ferreira